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Visiting in Morning program Pajović explains that changes that occur in genes, for various reasons, increase the risk of developing covid-19 disease. These are multifactorial diseases, which include cardiovascular diseases, diabetes, neurodegenerative diseases.
More than 100 diseases, he adds, that are frequent in the population are multifactorial diseases.
“The probability of contracting kovid-19 depends on three factors. From our genetic predisposition, the circumstances in which we live and the way we live ”, points out the director of the Vinca Institute.
According to her, circumstances include environmental factors and the environment and how it affects whether the so-called bad genes that each of us have within the genome will manifest.
External environmental factors can also influence the expression of bad genes or their suppression.
The third factor is the way of life, and that means how we eat, what bioactive components food contains, mainly antioxidants, how long we sleep, what is our physical activity.
Recent research shows that the use of 500 milligrams of vitamin C, 1,000 to 4,000 IU of vitamin De has been shown to be an exceptional preventative.
“Quality of life is what can influence whether we increase or decrease our own risk of getting kovid-19,” says Pajović.
He adds that research has shown, especially in Italy and Spain, that people who have type A blood are much more likely to get sick than those with type 0 blood.
“This is explained by the way in which antigens, which are found on the membrane of erythrocytes, are proteins that are also encoded by genes,” explains Snezana Pajovic.
He adds that we are reaching the genetic level again because our blood groups are genetically determined.
Realization of three projects related to kovid-19
Within biomedical research, which refers to kovid-19, three projects are underway, says Pajović.
“They are projects that were obtained through a public call from the Scientific Fund. The duration of these projects is 18 months and we can come up with a concrete result in about 10 months ”, says the director of the Institute.
It emphasizes that within the program related to the selection of existing drugs, which can be reused, that is, applied in clinical practice, they have already obtained certain results.
In collaboration with the University of Texas College of Chemistry and Drug Reference Laboratory, they have published six international papers.
As for finding a cure for kovid-19, it will be, as she said, in another phase. Now that the epidemic is at its peak, it takes 10 years to find a new cure, and it costs around two billion dollars.
“We urgently need a solution. An innovative computing methodology has been developed at the Vinca Institute, on the basis of which we select existing drugs, and this project is being developed through cooperation with the University of Texas covid reference laboratory.” Pajovic said.
“After the selection of the drug, the second experimental phase begins where these drugs are used for experimental biochemical research, in several animal models and this covers part of the preclinical research using one of the most infectious mutants to obtain a clearer answer when it is an intense infection. ” , says Snezana Pajovic, director of the Vinca Institute.
