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We observe, looking around us, that there are still cases in which people do not feel “very well”, they do not have the symptoms that they consider typical of kovid 19 – cough, loss of the sense of smell and taste, and we conclude that they do not It is a crown; it is the problem of the common cold. Well, some have other symptoms after seven days. However, if they turn out to be positive, in that “lost” period, when they had “just a cold,” they were the most contagious and, if they did not isolate themselves, they put themselves and others around them at risk. The problem is that the crown gives a wide range of symptoms, and the course of the disease itself is quite individual.
Why does the crown attack all organs?
– The virus is, in essence, a parasite that needs a host in order to multiply and spread. And you can enter the house only if you have a lock (ACE2 receptor, a protein on the surface of a human cell) and a key (protein on the surface of a virus). When they match, the door opens for the virus to enter our cells. Unfortunately, the cells of our respiratory tract have these receptors and that is why pneumonia is so common in kovid 19. However, many other organs have them: heart, brain, small intestine, liver, kidneys, eyes … That is why kovid 19 is not only respiratory. disease, can already affect many organs and give different symptoms and clinical pictures.
Does more than 60 deaths a day mean that the virus is stronger now?
– Many studies are concerned with ACE2 receptors and until now it has been assumed that differences in the structure, number and availability of cells, which exist naturally between humans, are partly responsible for the course and outcome of covid 19. Comparisons Scientific studies of SARS-CoV-2 with “close cousin” that caused the SARS epidemic in 2003 (SARS-CoV 1) showed that today’s corona, which binds to the same receptor, does so much more strongly and efficiently. However, the mortality of SARS-CoV 1 was much higher (on average 10-15%), while for the current corona the average is 0.3-3.3%. So far, science has not determined that this virus has significantly changed in “strength.” Mortality depends on many parameters, including healthcare, therapy, whether someone got to the doctor on time or waited too long, the patient’s previous health, age … Unfortunately, more than 60 deaths a day means that we ignored him. that we have all relaxed and that part of the population still does not understand the seriousness of the situation, nor is it aware of the consequences of our (non) action. The virus has spread uncontrollably to the entire population, and that is why we have a large number of infected people, but unfortunately, also dead.
With nearly 8,000 infected a day and epidemiologists’ claims that this number is realistically 10 times higher, are we on the right track to gaining herd immunity?
– Herd immunity is achieved when, without any intervention, and what is very important, an infected person in the population transmits the same infection to less than one person. This means that the virus cannot spread further because it encounters resistant people. So far, most scientists agree that it is necessary for at least 50%, and some up to 60-70% of the population, to acquire immunity to stop the virus. Although this has been debated as a possible model in some countries, most scientists agree that achieving herd immunity naturally is extremely risky, uncertain and irresponsible because it involves a significant number of deaths, hospitalizations and those that require hospital treatment. long-term. Also, the starting point here is the assumption that if a person becomes ill with kovid 19, they automatically become immune to that virus and that immunity lasts for a significant period of time. However, it is still under investigation. And one of the problems is that this virus is not as seasonal as, say, the flu and is active globally throughout the year regardless of temperature, which means there must be active protection throughout the year. The number of 8,000 infected per day, or indeed a much higher number, is not a “good” form of herd immunity, but a current situation for which we do not have an effective solution.
So only the vaccine is salvation.
– It is very good news that the world is working on the development of more than 150 different vaccines, and a significant number of them are already being tested in the third phase. This whole process normally takes an average of 10 to 12 years, but since we are in extraordinary circumstances, everything is incredibly fast and the first approved vaccines are expected in late 2020 and early 2021. Of course, it will take time to produce the first quantities. are distributed throughout the world. And you have to wait and see the effects over time. To begin with, the most important thing is to reduce the severity of the clinical picture and mortality among high-risk groups and to provide protection to healthcare workers who are directly exposed to the virus. The first vaccines should be a tool in the fight against kovid 19, and we cannot expect that, like a magic wand, they will solve everything overnight. But the good and encouraging news is that after just one year of development, we are still close to them.
Vaccinations
A broad range
We will have a wide range of vaccines. Some of these vaccines contain dead or attenuated particles of the CoV2 virus itself, others a part of the virus (protein or part of it) that elicits an immune response or that protein is incorporated into another harmless virus for humans.
New technologies have also enabled the development of vaccines that contain only the genetic material of the virus (in this case mRNA), which instructs our cells to temporarily synthesize the virus protein, leading to the development of immunity.
JS Spasić
delivery courier
Author: delivery courier
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