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The new coronavirus pandemic has brought new discoveries every day. Neuroscientists at the Federal University of Rio de Janeiro (UFRJ) draw attention to the fact that the central nervous system can be affected by covid-19, along with a large series of international publications.
According to pathologist Dr. Carlos Senne, president of Senne Liquor Diagnostic, a reference center in Brazil for the collection and analysis of cerebrospinal fluid, there is an increase in the number of patients who, after developing the disease, have presented neurological symptoms such as For example, headache, generalized fatigue, seizures, in addition to other manifestations resulting from the evolution of the disease caused by the virus, such as Guillain-Barré syndrome.
Little is known about the influence of the SARS Cov-2 virus on the central nervous system. Encephalitis, which results from inflammation of the brain parenchyma and may be caused by infections or autoimmune conditions, has been reported to be associated with covid-19. A recent publication links acute necrotizing hemorrhagic encephalopathy with the disease. In this publication, the researchers alert doctors and radiologists to patients with covid-19 and altered mental status.
“In cases where the patient has these symptoms, extensive investigation using diagnostic imaging, preferably magnetic resonance imaging, is required, along with laboratory tests of cerebrospinal fluid or cerebrospinal fluid. This evaluation is essential for the diagnosis of disease. that act on the central nervous system, “he explains. Molecular tests, such as real-time PCR performed on CSF, aid in the diagnosis and detection of the presence of infectious agents that cause disease, covid-19.
Diagnosis
The most widely used procedure to collect CSF is through a puncture in the lower back. The CSF collection made by a specialist doctor provides benefits, minimizes risks and guarantees patient safety. “As the evolution of the conditions is generally rapid, the agility of the diagnosis for the start of the appropriate treatment is essential to avoid irreversible neurological sequelae and save lives,” warns the clinical pathologist, former president of the Brazilian Society of Clinical Pathology.
The examination is carried out on high-tech equipment, such as the BD MAX ™ system. It is an automated platform that performs nucleic acid extraction and PCR in real time. With full automation of the process, the flow is standardized, reducing the possibility of errors and with the release of faster results and reducing errors. It is possible to run tests simultaneously for up to 24 types of samples of various syndromes and provide the results in up to four and a half hours.
“The solution optimizes the workflow of the teams involved in the diagnosis, decreases the response time for decision-making by choosing the right treatment, thereby reducing the total cost of treatment for the patient,” says Senne.
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