Understand if someone who has a mild Covid symptom may have a severe reinfection



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Covid-19 figures updated throughout Espírito Santo
Covid-19: Experts warn that anyone who has had the disease is not safe. Credit: Pixabay

According to microdata from the Covid-19 Panel, released by the State Department of Health (Sesa), more than 16,000 people in Espírito Santo had a positive PCR test without having presented any symptoms. Of the people considered infected at some point, more than 49,000 were considered asymptomatic.

A gazette listened to the experts to understand if a reinfection in these cases would necessarily be accompanied by symptoms and with possibilities of greater severity than the first contamination.

According to infectious disease doctor Lauro Ferreira Pinto, the Fiocruz study shows something that has already been scientifically reported, as similar research is being carried out in other parts of the world.

“There is a study published by the Oxford group on the 23rd in the New England Journal of Medicine, which is the most important American medical journal, in which 12,000 health professionals were followed over a period of 6 months. The research He showed some things and one of them is positive: reinfection is not common and it is important to say it so as not to terrorize people ”, he highlighted.

Although it is rare, another fact is that there is a reinfection. “It can be milder or more severe. There are milder cases of reinfection, like the most classic case of a person who arrived at the Seoul airport in South Korea and had had a coronavirus in the past. The airport test showed that it was It was contagious again and had no symptoms. But there are more serious cases and there is at least one case of reinfection that caused death, in the case of someone who had a severe immunodeficiency and died “.

For the specialist, Fiocruz’s work indicates that people who have had milder cases are more subject to reinfections, as the Oxford study also showed.

“Antibody testing, like the one carried out by Abbott, appears to show some degree of protection. What the Oxford group has shown is that people who have antibodies at good levels in their blood are more likely to be re-infected, although not. are Impossible. But this is more common when the antibodies disappear. Despite this, the risk seems to be higher in those who had milder cases and the antibodies disappeared more quickly, “he pondered.

IMMUNE MEMORY APPEARS TO LAST 6 TO 8 MONTHS

According to the post-doctorate in Epidemiology and professor at the Federal University of Espírito Santo (Ufes) Ethel Maciel, who is a consultant for the World Health Organization (WHO), it is not yet possible to categorically affirm that a second coronavirus infection is in fact. more serious.

According to her, immune memory seems to last between 6 and 8 months, as some studies indicate. Therefore, you understand that until now there is no consensus on the effects of a second Covid-19 infection.

“Some people who were infected at the beginning can become infected again now, but this question of being more serious a second time is not yet a consensus in the scientific literature, because some reported cases were not more serious. We need to better monitor these cases in order to be able to assert with certainty “he asserted.

Ethel Maciel, consultant to the World Health Organization (WHO)

Post-doctorate in Epidemiology, professor at UFES and WHO consultant

“What we can say is that there is an alert that people who have had the mildest or asymptomatic disease (or even more serious), continue to implement all preventive measures. There is a reinfection and it may be more serious.”

THE FIOCRUZ STUDY

The survey followed four asymptomatic individuals weekly since the start of the pandemic in March. During the investigation, serological tests and RT-PCR were performed on the people monitored.

By sequencing the genomes, the researchers confirmed that one person contracted the virus associated with a genome imported into the country and another had a viral structure associated with the genome that was already circulating in Rio de Janeiro. All subjects tested positive for Covid-19 and were asymptomatic.

According to the foundation’s disclosure, according to Thiago Moreno, one of the people followed again sought out the research group at the end of May, alleging stronger signs and symptoms of Covid-19, such as fever and loss of taste and smell. For the virologist, the work reinforced the notion that reinfection by the new coronavirus is possible, and that it is common among respiratory viruses, emphasizing that the first exposure to the virus does not form immune memory.

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