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The “Therapeutic solidarity trial”, a study led by the World Health Organization (WHO) in more than 30 countries, presented the results in a previous publication on Thursday (15). The research, which is awaiting approval by scientific journals and review by other experts, claims that four antivirals used against Covid-19 are ineffective: remdesivir, hydroxychloroquine, lopinavir / ritonavir (combination), and interferon beta-1a.
- “Solidaridad” is a global study with more than 30 countries, made in 405 hospitals;
- It is a randomized trial Golden pattern, which has the strictest standards for the collection of scientific evidence;
- He participated 11,266 adults: 2,750 took remdesivir; 954, hydroxychloroquine; 1,411, lopinavir; 651, interferon plus lopinavir, 1,412, interferon only; and 4,088 were part of the control group, which did not receive the drugs.
- Outcome: 1,253 deaths were reported during the survey. The evidence indicates that Medications played little or no role in reducing Covid-19 mortality or length of stay.
According to the WHO, even if the trial still needs analysis by other scientists, it has already produced “conclusive evidence” about medicines.
“The progress made by the ‘Solidarity Therapeutic Trial’ shows that large international trials are possible even during a pandemic, and offer the promise of answering critical public health questions about treatment quickly and reliably,” says the text published by the organization.
‘No country out of danger’
On Monday (12), the WHO emergency director, Michael Ryan, said that recent data shows a stabilization and decline in the cases of Covid-19 in Brazil, but warned that this trend occurs based on figures “very, very high “.
“No country is out of the woods yet” – Michael Ryan, WHO Director
WHO says stability of pandemic in Brazil is positive, but numbers remain high
In the last week, Brazil exceeded 150 thousand deaths caused by the new coronavirus and still exceeds 5 million cases of Covid. Despite the high numbers, the moving average for deaths was below 600 for the first time since May, according to the media consortium.
The emergency chief recalled that Brazil is a country of continental proportions and local authorities must be alert. “To say that the disease is decreasing in Brazil is a positive thing,” Ryan said.
“(But) there must be a high level of mistrust as the (overall) numbers fall to ensure that areas are detected where they may be increasing,” said the WHO emergency director.
“As we have all learned under severe pain in recent months, the fact that the disease is in decline does not mean that it will not get worse again. … We must remain vigilant” – Michael Ryan, WHO Director
