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Patients with viral hepatitis are one of the categories of people most at risk for COVID-19, according to the United States Center for Disease Control and Prevention.
The other risk categories are the same as those published by the UK National Institute of Health (NHS), with the mention that the risk age threshold falls from 70 to 65 years.
List of categories of people at high risk of disease with the new coronavirus
The UK National Institute of Health has recently released a large list of categories of people at high risk of contracting the new coronavirus due to pre-existing medical conditions, such as:
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Chronic (long-term) respiratory diseases, such as asthma, chronic obstructive pulmonary disease (COPD), emphysema, or bronchitis
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Chronic heart disease, such as heart failure.
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Chronic kidney disease
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Chronic liver disease, such as hepatitis.
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Chronic neurological disorders such as Parkinson’s disease, motor neuron disease, multiple sclerosis (MS), learning disability, or cerebral palsy
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Old diabetes
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Spleen disorders: for example, sickle cell disease or ruptured spleen
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People with weakened immune systems as a result of conditions like HIV and AIDS, people taking chemotherapy or steroids.
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Overweight people with a body mass index (BMI) of 40 or more
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Pregnant women
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People over 70 years old.
The most serious manifestation of COVID-19 infection may be SARS: severe acute respiratory syndrome. Based on this fact, the World Health Organization has published a recent study on three cases of people who, according to the WHO, have been classified according to the pathology of SARS and who have viral hepatitis.
Liver failure is a common disorder and has been reported in up to 60% of SARS patients. Most of these patients have been treated with antibiotics, antiviral drugs, and steroids, which are potentially hepatotoxic. Therefore, it cannot be stated with certainty whether SARS-CoV infection can cause liver damage in itself, but the drug certainly hinders normal liver function.
The study findings revealed that SARS-CoV can settle in the liver and can cause mild to moderate inflammation and lobular apoptosis. The presence of prominent mitosis among hepatocytes possibly due to the hyperproliferative state and cell cycle arrest is an essential feature of liver pathology in SARS. With a better understanding of the pathology of SARS-CoV infection, including the probability of viral replication in hepatocytes, specific therapies can be discovered to reduce viral replication and improve the clinical course of the disease.
Additionally, some people living with hepatitis B and hepatitis C also have other conditions, such as high blood pressure, cardiovascular disease, and diabetes, and therefore have an increased risk of developing a serious form of COVID-19 infection.
Therefore, according to the authorities, the entire population must comply with the measures imposed by the military ordinances issued up to now, but the categories with high risk in case of infection with SARS-CoV must be more careful and aware of the risks that they can be exposed, they must inform themselves from official sources and obey the recommendations of specialists.
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