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The United States Food and Drug Administration (FDA) recently approved the COVID-19 vaccine developed by Pfizer. The serum produced by the Moderna company also received a favorable opinion. Both vaccines have a similar structure, but also notable differences, reports the EFE agency, cited by Agerpres.
The serum developed by Pfizer and BioNTech is already used in the US, Canada, but also the UK, while Moderna has just received approval.
What are the differences between the two coronavirus vaccines?
Store cold
The main difference between the two vaccines is cold storage. The Pfizer vaccine requires temperatures between -60 and -80 degrees Celsius, which requires the organization of an expensive and complex distribution and storage system, while the vaccine developed by Moderna requires a temperature of -20 degrees C and storage. in a normal freezer.
Aside from super freezers, the Pfizer vaccine can last 5 days in a normal refrigerator, while the Moderna vaccine lasts up to 30 days. Therefore, the vaccine is much more manageable logistically, especially for developing countries.
Dose administration
The two vaccines will be administered in two doses, but Moderna’s are 100 micrograms and must be administered 28 days apart, and Pfizer’s are 30 micrograms and require administration at a difference of 21 micrograms. of days.
The effectiveness of vaccines.
Both vaccines were nearly 95% more effective than expected, but Moderna has demonstrated its ability to prevent severe cases of COVID-19, according to FDA data.
Structure
Both vaccines use messenger RNA, or mRNA, which is introduced into human cells so that the body can produce viral proteins that serve to generate antibodies that the body needs to defend itself.
However, each vaccine uses its own type of lipid coating to protect messenger RNA.
Years
The FDA has approved the vaccine developed by Pfizer for those over 16 years of age, while the one developed by Moderna is intended for those over 18 years of age.
type of company
While Pfizer is one of the largest pharmaceutical companies for 170 years, Moderna is a biotech company founded only ten years ago and with no product on the market.
Modern, until recently a start-up, has so far not submitted any vaccines to the FDA.
Financial support
Moderna was actively involved in the Trump administration’s Operation Warp Speed (a public-private partnership initiated by the US government to facilitate and accelerate the development, manufacture, and distribution of COVID-19 vaccines) and agreed to 2,500 millions of federal funds to buy new equipment and expand its facilities.
In contrast, Pfizer was not involved in the public operation, but entered into a contract with the United States government to purchase 100 million doses of vaccine.
Publisher: AA
