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The statement comes days after the company and the university described the vaccine as “extremely effective” without mentioning why some study participants received lower doses of the vaccine, biziday.ro said, citing the Financial Times and The Telegraph. .
The mentioned source also shows that nearly 3,000 people received a half dose of vaccine followed by a full dose, and 8,895 people received two full doses. The surprise came from the fact that the group of volunteers who received a lower dose and a full dose, one month apart, in the booster, appeared to be much better protected than the volunteers who received two full doses. it was 90%, in the second only 62%.
The experts, also shows biziday.ro, raised doubts about this result, especially since the University does not know why the efficiency was higher in the group that accidentally received only half the dose of vaccine in the first vaccination. .
Oxford notes that it has discussed the issue with regulators and that it has been agreed to complete phase II testing in the two separate groups.
The real problem is that none of the 2,741 people in the group who initially received a lower dose is over 55 years old. Younger people tend to provide a stronger immune response than older people.
Another point of confusion comes from the decision to collect the results of two groups of participants who received different dosage levels to achieve an average efficiency of 70%.
According to the cited source, AstraZeneca shares lost more than 6% after the announcement, in the London market, and analysts believe that the vaccine is unlikely to obtain approval in the United States.
US authorities question its effectiveness, especially since the best results were obtained in a small group of people under 55 years of age.
Read also:
A Romanian researcher from Oxford explains the advantages of the Covid-19 vaccine developed by AstraZeneca: “It will not require the same restrictive conditions”
How the Oxford vaccine was 90% effective. The discovery, made by mistake
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