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Yes, in fact, it can be said that cancer disease is genetic, because it occurs when changes occur in the genetic material – the cells in the brain – and the cell begins to multiply incessantly and without stopping. Like humans, when they develop changes in their brains during adolescence.
Only the oncological disease is not necessarily determined and inevitable or, they do not give it supreme, hereditary force. Usually, those changes in genes are caused by our longevity: cells age, they multiply by errors, like typing quickly on a keyboard, those errors are reviewed and we have an unstoppable criminal.
Nature is not stupid, she knew that we were negligent and did not pay enough attention to each other, so the genetic information was doubled. We carry DNA, a two-stranded nucleic acid in which information from one strand is duplicated by another strand. He looks like a man taking care of a wife at a party: both the slippage will correct itself and the meager squeals will not allow it to get up, and the dirty joke will be silenced. Just as a multiplied Peter won’t do anything on vacation while his wife is next, a mutated gene won’t have much of an impact as long as it’s duplicated by his other chainmate.
Cancer
However, if Peter is angry enough, remembering that “the man is or is not man”, he will be much stronger physically and spiritually inferior to his other half: he will become dominant. Only a blunt force will turn off the one who stopped him and change the banquet table. For a dominant mutation, there is no second gene: it takes over the cell on its own and begins to multiply continuously.
Another scenario is when a man is not so aggressive, but his wife is tired of constantly caring for a spouse who has never married, mutters a “stream” and throws herself into the whirlpool of the ball. Although without aggression and dominance, the genes of both chains mutated and again, like society, the body’s cell does not change for the better.
This is how proto-oncogenes work, the genes responsible for cell growth and division. When regulation is disrupted and the “gas bottom” is constantly pressed, we have cancer.
Another scenario is impaired gene inhibitors.
If, on the occasion of the party, a neighbor who lives outside the border and cares with zeal for the spiritual and moral appearance of his neighbors summons the police in time, the celebration will stop and the family’s fate will be saved. Even if Grandma is asleep and doesn’t hear the intrusive cacophony of fun, she can still be woken up by her companion, an annoying barking little dog. However, if both Brisius and the neighbor fail to do their duty in time, both cells will once again be doomed.
For some, mutations occur earlier, for others later. Some are more prone to disease, others are more protected. It depends on both the environment and the genetic information we inherit. We will talk about the impact of the environment and cancer myths in upcoming shows, and about heredity today.
DNR
If a person is born with a gene already damaged in one of the two chains, the chances of getting sick are much higher, because there is no need to wait for both chains to mutate, only one remains healthy. In our example: if the wife stayed home, Peter had much more freedom at the party.
The more mutations, the sooner the disease will be revealed. And if mutations are dominant, sometimes you get sick even before you’re born.
The longer we live, the more likely that both circuits will mutate in the same places (if Peter wakes up at a party in the morning, the chances of making money are higher than after an hour). To this day, the perceived boundary between sporadic (accidental) and hereditary (familial) malignancy is considered to be fifty years old. After mentioning the date of the round, there is a greater chance that the cells are simply tired and changed, and before that, that inheritance is possible. Yes, that limit is very slippery, so family history, disease incidence, and “related” disease cases are evaluated at all times.
For example, breast, ovarian, and certain prostate cancers can be due to a mutation in the same gene, or recurrent thyroid, parathyroid, and adrenal tumors can also be the result of a single inherited mutation.
Cancer
The more unique sites or related oncologies on the same side of the family (maternal or paternal), the younger the disease is diagnosed, the more specific changes found in tumor cell research, the greater the possibility of inheritance.
These risks are studied and such diseases are diagnosed by oncogenetics, specialists in hereditary oncology. The indications of when to apply vary for each oncological condition, so it is best to consult your doctor.
However, if the oncological disease:
determined up to 40 years;
determined up to age 50, but there are close relatives with the same disease in the same family line;
many close relatives of the same line with the same diseases, regardless of age;
vulnerable paired organs on both sides (such as the breasts or ovaries);
the patient belongs to a genetically reduced group (such as Ashkenazi Jews);
there are specific changes in the altered cells
The oncogenetic consultation will certainly not confuse. And if only one grandparent was prescribed oncology when he crossed the 90-year threshold, there is hardly any risk of inheritance. And remember, it is always better, if possible, to test a sick family member than a healthy family member, so there is a higher chance of getting mutations.
I want Peter, our body, to be calm and familiar, but let’s not lose our vigilance.
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