State Medicines Control Agency: Reactions to AstraZeneca are almost indistinguishable



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“Like other vaccines, AstraZeneca has very similar side effects. These include pain at the injection site, fatigue, headache, muscle and joint pain, and fever,” explained a senior advisor to the Pharmacovigilance and Poisoning Information Unit. the Medicines Control Agency.

According to her, the main difference between the vaccines currently in use is that reactions to the AstraZeneca vaccine are more common after the first dose, and reactions to the Moderna and BioNTech vaccines are more common after the second dose.

“Reactions after the second dose of AstraZeneca are milder and less frequent. We hope to see that in the future when the second dose of vaccination begins, but it has already been confirmed in clinical trials,” he said.

Questions about the vaccine from the British and Swedish company AstraZeneca arose after the European Medicines Agency authorized the vaccine in late January, noting that there were not yet enough studies on whether the vaccine provides effective protection to people over 55.

Subsequently, discussions about the side effects of the vaccine were shared on the social networks of some vaccinated people.

As reported by the Drug Control Agency on Monday, 802 reports of adverse reactions to COVID-19 vaccines were received between the start of vaccination and mid-February.

The vaccine received 585 notifications for the vaccine developed by BioNTech and Pfizer, 34 notifications for the Moderna vaccine, and 172 notifications for the AstraZeneca vaccine.

According to R. Pilvinienė, more than 163 thousand people were injected during this period. BioNTech and Pfizer vaccine doses, more than 9 thousand. Modern doses of vaccine and around 14 thousand. AstraZeneca vaccine dose.

“While BioNTech and Pfizer and Moderna received 3-4 reports for every 1,000 vaccines, AstraZeneca received 12 reports,” said a spokeswoman for the Medicines Control Agency.

He also added that vaccination with the latter vaccine had only just begun, and that the number of reports was similar to that obtained when BioNTech and Pfizer were vaccinated, with around 140 reports received at that time.

“One important thing is that the number of reports is not equal to the frequency of adverse reactions. We are just talking about people being as active as they are. The exact frequency of cases is determined in clinical trials. (…) In in this case, we are talking about the frequency of complaints, not the frequency of cases. We cannot compare the safety of vaccines from these data, “said R. Pilvinienė.

No vaccine provides absolute protection

According to the Medicines Control Agency, 760 notifications are classified as mild to moderate and 42 as serious.

The most serious reactions so far have been reported with the BioNTech and Pfizer vaccines.

“But it is this vaccine that has given more injections, so it is natural that the more vaccines, the more reactions and the greater the variety,” said R. Pilvinienė.

Following the outbreak of a coronavirus outbreak at the Addere nursing home in Trakai this week, three of the infected population were diagnosed with COVID-19 after two doses of the vaccine.

A spokeswoman for the Medicines Control Agency said such cases were not impossible because no vaccine provided absolute protection.

“Nowhere is it stated that the protection with any vaccine is 100%. (…) A person can get sick despite having been vaccinated, but they can get sick in a milder way. That is what is sought and is wait, ”he said.

According to data from the Department of Statistics, in Lithuania, the first dose of the COVID-19 vaccine was administered to 125 thousand people. 518 people, in both doses: 68 thousand. 651 people.



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