Professor Čaplinskas details what happens in the body after being vaccinated with a coronavirus vaccine



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Opponents of the vaccine also drew attention to the possible side effects of the vaccine, especially since there have been reports of an allergic reaction in several people who have been vaccinated.

Professor Saulius Čaplinskas, a specialist in infectious diseases, told the Delfi portal that such a vaccine against the coronavirus is indeed particularly safe, and that any vaccine can have side effects, but this is not necessarily a bad thing.

“These vaccines are especially safe because they contain no preservatives, no antibiotics, no DNA, no other stuff: monkeys or other leftovers, gluten-free or egg white, and of course there are no chips and they can’t be, as someone imagines.” , “The professor explained.

S. Čaplinskas reassured: The BioNTech and Pfizer vaccines cannot replace human DNA, because the mRNA they contain is very unstable.

“If you just injected it, various enzymes would eat it right away. Instead, it is incorporated into nanoparticles, special lipids. There is nothing new here. It is the science that makes it possible to transport a drug to a certain place, especially in cancer treatment Well, what led to the rapid development of this vaccine, because those technologies were already clear, “said the professor.

How BioNTech and Pfizer use Comirnaty

How BioNTech and Pfizer use Comirnaty

© S. Čaplinsko infographics

As mRNA is very volatile, as mentioned above, -70 ° C freezers are required for storage and transport of the vaccine. These special conditions make the vaccination situation very difficult. So although the technology has already been invented, such vaccines have not been developed before.

So how does the mRNA delivered to the cell by nanoparticles in the body work to produce the protein needed by the recipe encoded there? Can it affect our DNA in any way?

“It just came to our knowledge then. First: RNA cannot be incorporated into human DNA in any way. The second is that even in that lipid, RNA does not remain for more than a week. It is destroyed in a week and no longer it remains in the human body. RNA cannot harm in any way, “said S. Čaplinskas.

The professor emphasized that all components of the vaccine have no side effects, except that in some people lipids, those nanoparticles, can rarely cause certain allergic reactions.

In Lithuania, vaccinations against COVID-19 have started

In Lithuania, vaccinations against COVID-19 have started

© Santara Clinic

“And in other cases, when nanoparticles are used to transport other drugs to the right place, like a cancer cell, it is exactly the same: allergic reactions can occur. Doctors know it. They warn people with allergies, monitor them closely, and evaluate them. By the way, even very allergic people are sometimes prescribed such a drug, but it is immediately known how to treat such an allergic reaction.

Now, because everything is going public and everyone is interested in making vaccines as safe as possible. When it was announced that a total of 4 people in England out of 144,000 vaccinated had developed an allergic reaction that had no major consequences, it was immediately clear that allergic reactions to anything can develop anyway. But its side effects do not outweigh the benefits that the vaccine provides both to the individual and to society as a whole, ”said S. Čaplinskas.

According to the interlocutor, the side effects after administration of the vaccine are the same as for other vaccines: 2 to 10%. People may experience side effects such as pain at the puncture site, fever or fatigue, etc.

“It just came to our knowledge then. For some it gets that expression, and for others it doesn’t feel anything. And the question is better: not feeling anything, or feeling some kind of reaction from the body, because it means that protection, antibodies and cells are produced. by heart, ”said the professor.

S. Čaplinskas, a professor at BioNTech and Pfizer, described more about how it works on his Facebook account of the social network.

What Pfizer-BioNTech COVID-19 contains

What Pfizer-BioNTech COVID-19 contains

© S. Čaplinsko infographics

The professor wrote:

One of the most frequently asked questions today is: What is the composition of the Pfizer-BioNTech COVID-19 vaccine?

It is a SYNTHETIC VACCINE, whose components and functions are:

ACTIVE PART

– A modified synthetic information RNA (mRNA) molecule that encodes an analog of the peak glycoprotein (S) of the SARS-CoV-2 virus.

The mRNA sends a message to human cells about which specific viral proteins it needs to produce to trigger an immune response to the coronavirus (SARS-CoV-2). The mRNA is an unstable molecule, therefore freezers at -70 ° C are required for the transport and storage of the vaccine.

LIPIDAI

– (4-hydroxybutyl) azanodiyl) bis (hexane-6,1-diyl) bis (ALC-3015)

– (2- hexyldecanoate), 2-[(polyethylene glycol)-2000]-N, N-ditetradecylacetamide (ALC-0159)

– 1,2-distearoyl-sglycero-3-phosphocholine (DPSC)

– Cholesterolis

These are the names of four different water-insoluble fat (lipid) molecules. The mRNA molecule is unstable and is easily degraded by enzymes in the body, so it is encapsulated (inserted) into lipid nanoparticles. The composition of lipids is well thought out: some of them bind strongly to the mRNA molecule due to the opposite charge, others form the spatial structure of the liposome, which contains the mRNA. Lipids give the vaccine a whitish tint, help transport and protect the mRNA. This ingredient causes an allergic reaction very rarely.

SALT

– Potassium chloride

– Monobasic potassium phosphate

– Sodium chloride

– Basic sodium phosphate dihydrate

These are the names of the four salts in the vaccine. A mixture of these salts forms a phosphate buffered saline (PBS) that maintains the physiological pH of the vaccine. It is widely used in various injectable preparations.

SUGAR

– sucrose

It is the same sugar that we use to sweeten coffee or tea. Here, it serves as a cryoprotectant, ensuring that specially cold-stored lipid nanoparticles do not stick or stick to the packaging surface.

The vaccine does NOT contain:

live or attenuated viruses, human embryonic stem cells, DNA, antibiotics, blood products, preservatives, gluten, egg white, pork derivatives, microchips … ‘

It is strictly prohibited to use the information published by DELFI on other websites, in the media or elsewhere, or to distribute our material in any way without consent, and if consent has been obtained, it is necessary to indicate DELFI as the source. .



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