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Chills, headaches, and muscle aches are the most commonly reported side effects by volunteers vaccinated with vaccines from different manufacturers. Any unpleasant symptoms are reported to be short-lived and there are no concerns about the safety of such vaccines.
“It’s a really intriguing discovery, we didn’t expect it,” said Professor Matthew Shape, a member of the Oxford Vaccine Group.
The Com-Cov study, launched in February, looked at whether a second dose of a third-party vaccine could lead to longer-lasting immunity, better protection against new strains of the virus, and simply whether it was safe to vaccinate in absentia. of the vaccine.
The Canadian states of Ontario and Quebec say they plan to start mixing different vaccines in the near future. This decision was made due to Oxford-AstraZeneca’s supply problems and concerns about extremely rare blood clots.
The study, conducted by the University of Oxford, involved 830 volunteers over the age of 50. The first detailed results of the study are expected in June. Preliminary data is published in the Lancet medical journal.
One in ten volunteers who received two doses of AstraZeneca with a four-week break complained of a fever. When the volunteers received one dose of AstraZeneca and another dose of Pfizer, the ratio increased to 34%.
“The same tangible differences apply to other symptoms, such as tremors, fatigue, headaches, weakness and muscle aches,” Professor Shape said.
“That means we don’t want to vaccinate all the nurses with different vaccines on the same day because there may be lack of hands the next day,” says the professor.
The tests are reported to have been carried out across the UK, with randomly selected volunteers, writes cbc.ca. We will have to wait for more detailed results. The first phase of testing can only provide information on the side effects of vaccination and not on the safety and efficacy of vaccination with vaccines from different manufacturers.
“So far, we cannot say that such vaccination practices can improve the immune response. We will know more about this in a few weeks, “says Professor M. Shape.
Shape also says that this Oxford University study should encourage all regions considering vaccination with different vaccines to be better prepared for the possible consequences (more active side effects), which is especially true for hospitals where shortages staffing can have serious consequences.
As The Lancet notes, other studies are currently being conducted on the Moderna and Novavax vaccines.
Zain Chagla, a McMaster University professor and infectious disease specialist who was not involved in the study, says that determining exactly how many COVID-19 cases can be avoided by vaccinating people with two different vaccines will only be possible if we have plenty of time. term test results.
According to the expert, so far it seems that such a vaccination strategy in Canada may be justified, and he compared the most aggressive side effects to those in which a person who has already had COVID-19 reacts more fiercely to the vaccine.
“It just came to our attention then. After all, our main goal is the most effective response of the immune system,” says Z. Chagla.
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