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As multinational pharmaceutical companies are imminent to approve the urgent use of a new vaccine against the infectious disease coronavirus (Corona 19), interest is growing in the effectiveness, cost and advantages and disadvantages of each vaccine. The Pfizer and Modena vaccines are very effective, but are considered expensive and difficult to distribute. The AstraZeneca vaccine is somewhat ineffective, but it has the advantage of being cheap and convenient to distribute.
According to Reuters on the 23rd (local time), the immune effect of AstraZeneca and AZD1222, a vaccine candidate at the University of Oxford in the UK, averages 70%. In the test group that received half the dose (dose) and received another dose after one month, the immunological effect was analyzed to be up to 90%. It is less effective than the Pfizer-Bioentech (95%) and Modena (94.5%) vaccines.
The AstraZeneca vaccine is inexpensive. The company plans to set a price of $ 3 to $ 5 per dose of vaccine. Pfizer will supply the first 100 million doses at $ 19.5 per dose. In fact, it costs $ 39 per patient because it is necessary to receive 2 doses for the immune effect. Moderna is known for offering vaccines at a higher price.
The principle of the vaccine is also different. AstraZeneca places the inactivated coronavirus into the adenovirus that causes the cold and then injects it into the human body to elicit an immune response. Pfizer and Moderna chose the latest technology, such as the use of messenger ribonucleic acid (mRNA), which contains the genetic information of the virus. The mRNA vaccine has never been commercialized. Therefore, no country has experience in mass production.
The mRNA vaccine has the disadvantage of being weak against heat. Pfizer vaccine can be stored for up to 5 days at 2-8 degrees Celsius, which is normal refrigerator temperature, but must be kept between -60 and 80 degrees Celsius during distribution. The Modena vaccine is stable for 6 months at -20 degrees Celsius and 30 days at 2-8 degrees Celsius. AstraZeneca vaccine can be transported, stored and administered at 2-8 degrees for at least 6 months.
Reporter Park Sang-yong [email protected]
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