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High antibody titers developed 14 days after the first dose of the Pfizer / BioNtec BNT162b2 mRNA vaccine in 92% of the vaccinated healthcare workers at Gennimata Hospital in Thessaloniki. This is derived from the results of the measurements that were carried out last January in Gennimatas to 425 health workers, aged 21 to 67 years. This study is phase 4 and it is the first pre-published study in our country that includes such a sample size (425) and one of the few in the world.
Since 425 people were vaccinated, 362 who had no history of COVID-19 developed antibody values ranging from 50 to 3990 AU / ml, while only 33 people with no history of disease had low antibody titers (<50.0 AU / ml). Note that 63 of those vaccinated had a recent history of COVID-19 and all developed very high antibody titers ranging from 10,250 to 80,000 AU / mL. In terms of age, antibody titers did not differ between the ages of 20 and 50, however, in the 50-60 age group, antibody titers showed an even greater downward trend in those older than 60 years. Measurements are already being processed 14 days after the second dose in which the antibody titers are expected to multiply and the measurements will continue 3, 6, 9 and 12 months after the second dose.
About aside effects none of those vaccinated had an anaphylactic reaction or any other serious side effect. The reported side effects were the usual ones seen with vaccines (injection site pain, diarrhea, myalgia, headache, low-grade fever) and were mild and transient.
The study coordinator was George Papazisis, Associate Professor of Clinical Pharmacology, Department of Medicine, Aristotle University of Thessaloniki, with Konstantina Kontopoulou (Director of the Microbiology Laboratory, President of ENL and coordinator of the 2 Vaccination Centers of the General Hospital). The members of the research team of the hospital “G. Gennimata” were Eleni Antoniadou (coordinating director of the UCI, vice president of ENL, president of the Scientific Council, Dr. Athena Yfantidou (Curator of Biopathology), Georgia Gologos Enanti (Kardiki), Vassilis Adamopoulos (Chemist) and Nikitas Papadopoulos (Nuclear Physician, Vice President of the Vaccine Coordination Group of the 3rd Health District).
The full article is freely accessible as a previous publication (previous printing in the SSRN database) at the link https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3786138
With information from the Athens / Macedonia News Agency
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