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During the period required for the human body to acquire immunity, after vaccination against the new coronavirus, it was mentioned in an article of the Professor Elias Mosialos, answering a key question, which concerns a significant part of the population of Greece.
More detail:
Moderna and AstraZeneca vaccines have a 4 week interval between the first and second dose of the vaccine and 3 weeks from Pfizer. Some people wonder about the differences in interval and protection after the first dose.
Let’s see what we know about the Pfizer vaccine.
While there is evidence of high levels of short-term protection with the first dose of the vaccine, what has been approved by the British authorities and is also expected to apply in Europe is the two-dose schedule. Both will be injected into the deltoid muscle (in the arm) and the second dose must be given at least 21 days after the first. For the Pfizer vaccine, the reported efficacy rate was calculated seven days after the second dose. That is, after 7 days, the antibodies seem to develop, but we may have to wait more than 7 days, preferably two weeks, to be sure.
Therefore, we remain vigilant at the start of the first dose for 4-5 weeks for the Pfizer vaccine and for 5-6 weeks for Moderna and StraΖeneca.
In other words, some protection may exist prior to this period, but this is the time that is considered appropriate for full protection to begin.
We will learn more about the scope of protection and its duration as data from current clinical trials is entered.
Based on data from clinical trials, the efficacy of the vaccine is 94% and 95% for Moderna and Pfizer, respectively. In other words, these are the expected protection percentages. But efficacy rates may be slightly lower when mass vaccinations are given, perhaps for the very old or the immunosuppressed. However, they do not expect these percentages to be much lower.
To certify if the vaccination, the antibody test should be done 2-3 weeks after the second dose.
Appropriate supplies should be made and the state should prepare for adequate antibody testing before and after the end of vaccination so that
1. Give priority to the groups to be vaccinated in the general population.
2. Confirm both efficacy and specific immune response rates by age group or patient group.
The final stage of your management pandemic you will need excellent and precise coordination. It will be a challenge for the health authorities, but also an opportunity to maintain the first national electronic registry of the disease, like all other countries.
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