The 10 innovations that will change Medicine



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Medical problems or, to be honest, the medical problem that monopolized 2020 was SARS-Cov-2. A virus nightmare, as it changed our lives unexpectedly, resulting in situations that until 2019 would be a sci-fi movie script.

Somehow, “what if …” turns into “what are we doing now” as our daily lives collide with the … wall of the pandemic, coming face to face with deadlocks. Fortunately, however, science is a driving force that has evolution at its core, that knows no limits or limits and does not accept that there are unsolvable problems.

Fatally, for about 12 months, we see an invisible enemy sink societies in conditions of insecurity. We are also watching with anxiety the tireless efforts of researchers to eradicate the pandemic virus by investing in treatments and vaccines.

And as everything shows, another impossible ακόμη will have occurred by the end of the year: by 2020 and early 2021 not only will one, but at least three vaccines have been produced, when as a general rule five ten years. Meanwhile, at least two more are close to cutting the finish line.

Thus, Medical Science enters the new year having gained knowledge and success in unimaginably concentrated time, resulting in a scientific feat.

However, despite the criticality of the period we are going through, requests and the drive for more developments did not “freeze” in the midst of a pandemic. In this context, the world famous American clinic “Cleveland” recently decided on the 10 medical innovations that will change to improve the way medicine is practiced in the new year.

1. Hemoglobinopathies (the best known are sickle cell anemia and thalassemia) are due to a genetic deficiency of hemoglobin, resulting in the production of reduced and non-functional red blood cells. However, an experimental gene therapy that prevents related complications appears to be very promising.

2. Multiple sclerosis is a chronic, autoimmune disease in which the immune system attacks the central nervous system. A subset of patients are diagnosed with primary progressive multiple sclerosis, which means that the disease progresses gradually without exacerbations or relapses. For these cases, the first and only treatment is a new therapeutic monoclonal antibody (approved by the US Food and Drug Administration – FDA).

3.Remote monitoring of implantable devices, such as pacemakers and defibrillators, is an essential part of patient care. Bluetooth technology allows patients and clinicians (via their mobile phones) to easily access data, allowing them to detect potentially dangerous events.

Four. The discovery of CFTR regulators marked a breakthrough in the treatment of cystic fibrosis, a disease that causes systemic respiratory infections that gradually reduce the ability to breathe. However, these newly developed drugs have been shown to be effective for a subset of patients. But a new combination of drugs appears to bring relief to patients with the most common mutation in the CF gene (F508 Del), which is estimated to make up 90% of people diagnosed with the condition.

5. As no vaccine has yet been found, patients who have been diagnosed with hepatitis C they are limited to medication, which is often accompanied by side effects or is effective for certain genotypes of the disease. However, a new fixed-dose combination drug has significantly improved treatment, as it appears to be 90% effective for genotypes 1-6.

6. Premature babies need specialized care, including babies with respiratory failure. In this setting and in contrast to mechanical ventilation, a recent, non-invasive method (b-CPAP) provides continuous positive airway pressure to newborns to maintain expiratory lung volume. Also, oscillation rather than constant pressure plays an important role in its safety and effectiveness.

7. The current pandemic has highlighted the need for a hybrid model patient monitoring. In particular, in addition to clinical examination, telemedicine proved to be an important “tool” in emergencies, as it was recognized as an effective virtual model of care for chronically ill patients.

8. Postpartum bleeding is an emergency and one of the leading causes of death in new mothers. As a general rule, its treatment is medical or surgical, while in recent years non-invasive methods (balloon) have been used that compress the bleeding point. The newer method is a plugging device that is inserted transversely into the uterine cavity. This new treatment uses negative pressure to force the muscle to close the blood vessels. It is an inexpensive, low-tech solution that can save lives in developing countries.

9. It is estimated that one in nine men will be diagnosed with prostate cancer at some point in your life. And while significant progress has been made over the past decade, the disease remains the second leading cause of death worldwide. But two PARP inhibitors, known to treat gynecological cancers, appear to significantly (and) significantly slow the progression of prostate cancer by changing the horizon of treatment.

10. About 1.2 million Greeks have migraines while in America, respectively, migraine affects more than 38 million people. However, it was not until 2018 that drugs exclusively against migraine were developed, interfering with the peptide associated with the calcitonin gene (CGRP) and which intervenes in the processes that “trigger” severe headaches. Actively prescribed in 2020 in the USA, this new class of drugs marks a new therapeutic era around the world.

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