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The first tangible proof that the coronavirus it can infect neurons in the brain through the mucosa.
Coronavirus can reach the human brain if it “enters” the human body through the nose and attaches itself to nasal mucus, as new research reveals.
One in three patients reports, however, symptoms such as loss of smell and taste, but also headaches, fatigue, dizziness and nausea.
Scientists in Germany, performed 33 autopsies on patients who died of coronavirus and examined the mucus in the back of the nasal cavity just above the mouth, at the point where the pharynx meets the nasal cavity, but also took samples of brain tissue.
Genetic coronavirus material It was found in large quantities in nasal mucus but also in the brain, spikes of the coronavirus protein were found that protrude from the virus and adhere to human receptors to infect cells.
How the virus reaches the brain
Dr. Frank Heppner, co-author of the study from the Charité University of Medicine in Berlin, noted:Once the virus enters olfactory mucosa, appears to use neuroanatomical connections, such as the olfactory nerve, to reach the brain».
At Research framework, the academics managed to capture the first electron microscopic image of whole coronavirus particles in mucus.
However, it is unknown at this time how the coronavirus from this point reaches the brain.
You can probably get through the blood vessels since the coronavirus was also found in the “walls” of the blood vessels of the brain.
The study was published in the scientific journal Neuroscience of nature and according to the cited data, it also detected immune cells in the cerebrospinal fluid, which were activated after infection.
Professor Heppner said:in our eyes the presence of coronavirus in the cells of the olfactory mucosa explains the symptoms of loss of smell and taste».
They have also been found in areas of the brain that control vital functions such as breathing.
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