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Two safe and effective vaccines, which are done during childhood, can provide some form of protection against young people crown SARS-CoV-2, which causes COVID-19 disease.
During yesterday’s briefing, the representative of the Ministry of Health for the new crown, professor of Infectious Diseases at EKPA, Mr. Sotiris Tsiodras.
As he characteristically said, “there is a great effort not to cancel the presence of the epidemic, the course of other vaccines that are important and save lives throughout the world and especially in underdeveloped countries, in developing countries.”
The importance of vaccination.
With this phrase, Mr. Tsiodras indirectly referred to the call that he has answered. World Health Organization (WHO), for the faithful observance of national population immunization programs to avoid the appearance of vaccine-preventable diseases (vaccine-preventable diseases, VPD), such as measles.
In fact, the WHO has issued relevant guidelines for immunization during the COVID-19 pandemic, according to which “immunization (mass vaccination) is a health service that should be a priority for the prevention of infectious diseases and should be carried out out without problems during the COVID-19 “pandemic.
But a Ministry of Health spokesperson for the new crown, on March 30, 2020, in the midst of the quarantine, recalled that “suspending vaccination can lead to the accumulation of crazy people. And it had recommended the timely vaccination of children up to two years of age, especially with respect to first-class vaccines, with a preference for multivalent vaccines.
Two old coronavirus vaccines
There are two vaccinations necessary for children. tuberculosis (BCG) and her measles, rubella, mumps (MMR). As Mr. Tsiodras explained yesterday, the two specific vaccines “have been found in epidemiological studies, emphasizing that they are epidemiological studies, which act as protectors. That is, countries with very high rates of vaccination coverage for BCG or measles, MMR , appear to have fewer recorded deaths than the coronavirus.
He added that there are at least 15 to 20 different reasons why this could happen, and emphasized that “it is not necessary that something we see in epidemiology have a biological correlation.”
The tuberculosis vaccine
However, BCG, the tuberculosis vaccine, appears to activate some very important internal immune mechanisms and its use has been found in previous studies to protect respiratory children in general from respiratory viruses.
The BCG (Bacillus Calmette-Guérin) vaccine was developed in the early 20th century and effectively protects 50% to 86% of adults and children from the mycobacterium of tuberculosis.
Researchers in Australia and the Netherlands are already planning clinical trials to see if it can protect humans from SARS-CoV-2. The reason for scientists is that the BCG vaccine boosts the immune system and, in combination with medications, is tested as a treatment for bladder cancer and melanoma, as it can push immune cells to attack cancerous tumors. But, as mentioned above, it is also good for the immune system of the lungs, since vaccinated children are less likely to become infected with respiratory infections.
In this context, scientists in Europe and Australia are preparing to administer BCG to people at high risk of disease, i.e. health professionals, in the context of randomized clinical trials. These phase III studies will determine if people vaccinated with BCG have a less common or less severe COVID-19 infection. If the vaccine is effective, the scientific community should clarify which of the many strains of the vaccine provides the best protection.
MMR vaccine
Researchers from the University of Cambridge in Great Britain say that the triple measles and mumps vaccine, MMR, could help the immune system treat SARS-CoV-2.
MMR is given to babies from childhood, and many scientists believe that because children get sick less often and are milder than COVID-19 disease, it may be due to the vaccine.
Analysis of the structure of the basic proteins of measles, rubella, and mumps has revealed that they bear an unexpected resemblance to specific SARS-CoV-2 proteins. In particular, the S protein (protein) of the new crown is 20% comparable to the measles “fusion protein”. However, it is unclear if this is sufficient to trigger a cross immune response.
Therefore, detailed clinical trials in large population samples will be required to determine whether a vaccination history against tuberculosis and mumps against measles or other diseases can reduce the severity of COVID-19 infection.
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