Corona Drug: “Remdesivir Works” – Coronavirus drugs may be available soon

A coronavirus medication is urgently needed. Now, the head of the German studio has said: “Remdesivir works” and may be available soon.

Update May 10, 2020: After the first promising results on the active ingredient in the United States a few weeks ago Remdesivir as a remedy for that Corona virus have been released, now there are positive signs from Germany: the preparation Remdesivir “We will be available in a few weeks or a few months,” says Gerd Fätkenheuer, chief of infectology at the University Hospital of Cologne, the Cologne City Gazette.

In Remdesivir It is an active ingredient that was developed against Ebola. Currently also being investigated in a study in Germany Crown crisis urgent Medication They are needed. The study is at a “very advanced stage,” says Fätkenheuer. “We can say: Remdesivir it works. “It has already been shown that Remdesivir at one Covid-19 disease soften and shorten the difficult course.

Remdesivir as a crown medication: unknown side effects

Essentials The side effects of remdesivir They are not known, but should be investigated further. Than Drug According to the calculations of a British researcher, the cost price of a ten-day treatment was around ten euros. “How expensive it will be to sell then is another question,” says Fätkenheuer.

The researcher warns against the Kölner Stadt-Anzeiger that this is Virus “The slide, like it’s under the radar, is spreading and there is a second wave that is mentioned over and over, that will have incomparably greater force.”

Remdesivir against coronavirus: a drug is urgently needed

First report of April 17, 2020: Originally the antiviral active ingredient remdesivir against Ebola developed but is now one of the Active ingredientsthose who have the highest hopes that they may be against Sars-CoV-2 coronavirus help At a Chicago hospital, American researchers are conducting a clinical study with the Drug through – apparently with promising results: as reported by the health portal “Stat”, there are several in the hospital Crown patients positive in Remdesivir answer back

Hospital doctors would see “a rapid recovery from fever and respiratory symptoms” in crown patients treated with remdesivir, “almost all patients” would be discharged from the clinic in less than a week, according to the report. Consequently, 125 people were with Covid-19 included in the clinical trial. 113 of these patients were “seriously ill”, the 125 patients received daily Remdesivir infusions.

Remdesivir help against Covid-19? Promising results from the US USA

There are also studies in other clinics in the US. USA, of which no results have yet been published. Gilead Sciences, the manufacturer of Remdesivir, he emphasized in a statement: “What we can say at this stage is that we are waiting for data from the other studies.” Previously, the data was expected in April. “Stat” assumes that clinical trial data could be published “at any time.”

“Most of our patients are seriously ill and most leave the hospital after six days,” says “Stat” portal Kathleen Mullane of the University of Chicago. Mullane said this in a video conference with other members of his faculty, a recording of which is on the portal and was later confirmed by Mullane. “Drawing conclusions” from the data is, however, “premature and scientifically unreliable,” “the University of Chicago said in a statement about the recording.

Active ingredient against the crown: look at the study remdesivir with caution

In fact, you must also have the data Remdesivir First look with caution: They have not yet been confirmed by an independent body, and more studies are still underway. Mullane continues on the video recording to consider that he is in the Remdesivir studio there is no placebo group to control.

The Active ingredient remdesivir integrates into RNA and inhibits the multiplication of Sars-CoV-2 coronavirus. Remdesivir is administered intravenously by infusion and is considered Broad spectrum antiviralthat could be effective against different viruses, in addition Sars-CoV-2 also against the related pathogens of Sars and Mers or the Ebola virus.

Coronavirus drug: Remdesivir not yet approved in Germany

Is allowed Remdesivir Not yet in Germany. In Germany, the active ingredient is currently available directly from the manufacturer in individual cases after a pre-test *. These are the so-called “individual healing attempts”. Since early April Remdesivir on the list of confirmed drug distress programs of the Federal Institute for Drugs and Medical Devices (BfArM). The WHO already prioritized research on remdesivir in clinical trials in January.

BfArM President Karl Broich expects the first results of the Covid-19 treatment trial in three months. Until then, the data would be out two great studios with remdesivir in Germany expected, Broich said. Overall, there are some promising therapeutic approaches.

Covid-19 drug is eagerly awaited

If Remdesivir is the long-awaited drug that works against Covid-19 help until a Sars-CoV-2 * vaccine is developed, should show next months. An effective remedy that the disease Covid-19 the relief could support efforts to prevent health systems from collapsing until a vaccine is developed.

By Tanja Banner

Studies give hope: The drug Remdesivir works in patients with Covid-19.

* fr.de is part of the national central editorial office of Ippen-Digital.