Biontech / Pfizer Corona Vaccine: Who Shouldn’t Get Vaccinated Today

The vaccine was injected about 42,000 times in Germany. What active ingredients it contains and who must be well informed before vaccination.

Mainz – one vaccine There’s never been anything like this before: BTN162, the Covid vaccine from Biontech / Pfizer, The first people to get vaccinated in Germany are based on a new gene-based mode of action. But what exactly are the ingredients? And who should prefer not to get vaccinated at first or only after consulting their family doctor? An overview:

The novelty of this is its active principle, which consists of 30 micrograms of messenger ribonucleic acid (mRNA) per dose. RNA, the basis of the viral genome, has been modified. The vaccine contains the model of the peak protein of the Coronavirus, that the body must produce itself and then fight. The antibodies and immune cells that are formed in the process then protect against Covid-19, for how long and to what extent is not yet known.

Biontech / Pfizer Corona vaccine requires extreme cooling

Because RNA is not very stable, it has to be vaccine be stored extremely cold. For added protection, RNA needs a coating, which also helps it penetrate cells. This shell is made up of lipid nanoparticles, tiny spheres, barely larger than the virus itself, three of these four lipids are artificial, the only natural fat they contain is cholesterol. Some experts assume that the cause of isolated severe allergic reactions after vaccination lies in these lipid globules. Polyethylene glycol (PEG) is particularly suspected. However, none of the lipids it contains are unusual substances; they are often found in medications or cosmetics.

Other ingredients of Vaccine are different salts, they are supposed to protect mRNA and lipids and the uptake of Vaccine promote in the body. Unlike some conventional vaccines, the mRNA vaccine does not require preservatives or active enhancers (adjuvants).

Biontech / Pfizer vaccine: what to consider when vaccinating against Corona

Even if PEG is the leading candidate for triggering individual cases of anaphylactic shock after vaccination applies, you don’t know for sure what led to it. Special caution is indicated in the case of severe allergy sufferers who have already reacted with anaphylactic shock to a vaccine, a medicine, or possibly a certain food such as shellfish. People with hay fever, allergies to house dust, or animal hair probably don’t have to worry.

Patients who are taking certain anticoagulants (anticoagulant medicines), for example to prevent stroke or thrombosis, should also consult their GP. That has to do with the fact that vaccine Injected into the muscle, usually the deltoid of the upper non-dominant arm. Because the muscles are well supplied with blood, there is an increased risk of bleeding when taking these drugs. The British regulatory authority writes that these patients can only be vaccinated after a careful risk-benefit assessment. In the recommendation of the Permanent Commission of Vaccination of Germany (Stiko) it says that they should vaccination With a very fine injection needle, a compress should be pressed firmly over the puncture site for “at least two minutes.”

Medical advice on the intake of anticoagulant medications.

A vaccination on or under the skin, as is possible with some alternative vaccines, exclude Stiko. However, with certain anticoagulant agents, such as “Marcumar”, an intramuscular injection is expressly excluded according to the package insert. But patients who are taking newer blood thinners like “Eliquis” or “Xarelto” should also seek medical advice. One possibility could also be to take the medicine before the vaccination stop for a few days; but that should never be done arbitrarily. The active ingredient AAS, which is also taken by many people as an anticoagulant, is not pharmacologically one of the anticoagulants.

Cancer patients: not represented in corona vaccine studies

There is no uniform recommendation for Cancer patient: interior. For this group, which was not represented in clinical studies, “there was no reliable data on the efficacy and safety of the vaccine,” says Susanne Weg-Remers, head of the cancer information service at the German Cancer Research Center. Therefore, it is unclear what about various cancer therapies, such as chemotherapy or targeted drugs. vaccination tolerate. Weg-Remers advises your treating physicians “to request an evaluation.” The Cancer Information Service can be reached every day from 8 am to 8 pm by phone at 0800-4203040 or by email at [email protected].

Biontech and Pfizer Vaccine: Who Shouldn’t Get Vaccinated?

Not vaccinated There should also be people already attending COVID-19 I was sick. However, experts assume that it is not dangerous if someone who has gone through an infection without being noticed is vaccination get. Pregnant women, as well as children and adolescents under 16 years of age, should not be vaccinated at the moment because they have not participated in previous studies. (Pamela Dörhöfer)

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