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A new coronavirus vaccine, developed by scientists at the University of Oxford in the United Kingdom, has shown promising results. The vaccine, which was applied experimentally to humans, was tested to see how it reacted to monkeys. Although the coronavirus was extensively injected into the monkey’s body after the vaccine, the scientists said it did not cause the infection.
The researchers tested the possible coronavirus vaccine on a small number of monkeys and found promising signs. Six rhesus macaques received half a dose of the currently human-tested vaccine in the body of a monkey.
Furthermore, the vaccine has been administered to rats. There, some animals were found to produce antibodies to the virus within 14 days of vaccination, and evidence of antibody production was found in all of them within 28 days.
According to research reports, single doses of vaccination were also effective in preventing lung damage in animals. Organs that may be severely infected with coronavirus infection were not damaged after vaccination.
The researchers wrote: “We found a significant reduction in the virus in the bronchoalveolar lavage fluid and the respiratory tract in animals vaccinated with SARS-Cavi-2 compared to other animals, and no symptoms of pneumonia were observed in vaccinated Rhesus macaques.” Significantly, the vaccinated animals showed no evidence of disease that improves immunity after viral challenge.
The researchers also found that viral infections in the lower respiratory system were significantly reduced. The vaccine is administered to prevent the virus from replicating below the respiratory tract. However, although the spread of the virus in the lungs could be prevented, it was not possible to reduce viral transmission from the nose.
“The results are very good news,” said Stephen Evans, professor of pharmacospeptiology at the London School of Hygiene and Tropical Medicine. The most important finding for me is the combination of viral load and considerable efficacy in subsequent pneumonia. However, there is no evidence to increase immunity.
At the moment it is unknown what he will do after leaving the post, but he is optimistic about the result. He expressed cautious optimism that the vaccine made at Oxford would be tested in humans.
Formula- Science Focus.
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