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Different countries and known and unknown companies are conducting various tests to make this vaccine. Rich countries are investing billions of dollars in advance to obtain the vaccines that are generating hope.
Bangladesh has also started various efforts to obtain the vaccine. A Chinese company has already received permission to conduct a clinical trial of its vaccine in Bangladesh.
A Bangladeshi company has signed an agreement to bring the vaccine to India when production begins. The government has also said it will send a letter to Russia for vaccination.
Bangladesh has already applied for the Covid-19 vaccine through the Global Access Facility (COVAX) under the Global Alliance for Vaccines and Immunizations (GAVI).
However, no one has a definitive answer to the question of when the approved coronavirus vaccine will be available to the general public.
Director General of the Department of Health, Prof. ABM Khurshid Alam told bdnews24.com: “No one can say that the vaccine has been successfully developed anywhere so far. There has been a second test, some are doing a third test. Our position is that Bangladesh is doing what it needs to do to get the vaccine and is not lagging behind any other country.
Now there are around two hundred studies in the world trying to make a vaccine for the coronavirus. Of these, six potential vaccines have reached the final testing stage.
How far is the vaccine?
The new coronavirus, which began spreading from China late last year and has taken over the world, has already infected more than 2.5 million people, killing more than 660,000.
Currently, there are about two hundred studies in the world that try to make a vaccine against this virus. Of these, half a dozen potential vaccines have reached the final testing stage.
Among them are the University of Oxford-AstraZeneca, Moderna, Pfizer, Cansino Biological, Synovac Biotech and SynoPharm, which are conducting trials of the third phase of their possible vaccine in several countries around the world.
And Russia’s Gamalia Institute has started commercial production with government approval without completing its third phase of the trial.
Before a vaccine is finally approved, a large number of patients must undergo a clinical trial, called a third-stage trial.
If you are successful in the third stage test, the countries participating in the test will issue an emergency authorization. Finally, the final approval of the World Health Organization will come.
Dr, Doctor of Philosophy and Letters from Cambridge, will come to the government of Bangladesh with advice and assistance in the coronavirus crisis. Mushtaq Hossain, who was once the former scientific director of IEDCR.
His suggestion is that the government should have all options in hand to get the vaccine as a priority once it is made.
He told bdnews24.com that if someone took the initiative to make a vaccine in Bangladesh, emphasis should be placed on taking the problem forward. It will increase the “scientific excellence” of the country.
“As a second priority, we must participate in the experimental implementation of vaccines in different countries. This will ensure availability. The more tests we do, the more availability will be guaranteed.
“It is unknown at this time what he will do after leaving office. Several vaccines will not be successful. We will know if there is a successful vaccine trial, it will not be too late.”
Russia has started large-scale production of the coronavirus vaccine without a third-stage test.
What is Bangladesh doing?
The World Health Organization (WHO) and the Global Alliance for Vaccines and Immunizations (GAVI) are working to ensure that effective coronavirus vaccines are available to people around the world.
The World Vaccine Summit was hosted by these two global organizations on June 4, so Prime Minister Sheikh Hasina also joined via video conference.
At that conference, a platform called ‘Covid-19 Vaccines Global Access Facility’, which is abbreviated as Covax, was unanimously developed.
At Gavi’s board of directors meeting on July 30, it was decided to deliver the Covid-19 vaccine to 92 low- and middle-income countries under the Covax Advanced Market Commitment (AMC) project. Bangladesh is also included in that list as a lower middle income country.
If the World Health Organization approves a vaccine, Gavie has set a primary goal of providing the vaccine to at least 20 percent of the nation’s population. That is why the probable time is set for the end of 2021, although everything will depend on the approval, production and supply of effective and safe vaccines.
According to Health Department officials, Kovacs has decided that countries with a per capita income of more than £ 4,000 will have to buy the vaccine. Initially, Gavie will deliver a certain number of free vaccines to countries with incomes below $ 4,000.
According to him, Bangladesh submitted a request to Gavi on July 9 through the Kovacs platform. Health department officials said they had accepted the request.
They say that if the World Health Organization approves any vaccine, Bangladesh can get 34 million doses of Gavi vaccine at a rate of 20 percent of the total population. And if the vaccine is given, it will be given initially to ‘front-line fighters’ fighting the coronavirus, including doctors.
However, the complete vaccine will be delivered to Bangladesh free of charge, or a partial price will be paid for it; That decision will be made after Gavi’s board meeting in September.
Currently, the government has to pay 10 percent of the cost of vaccination against various diseases that Gavi receives from Bangladesh, while Gavi pays the remaining 90 percent.
Health Department Director General Professor Khurshid Alam told bdnews24.com: “We have made preparations according to Gavi’s instructions. However, it is not yet clear when the vaccine will be available. We are doing our best. “.
Health Minister Zahid Malek told bdnews24.com that even if an effective and safe vaccine has not yet been developed, the vaccine promised by Gavi will arrive in Bangladesh in June-July next year. Before that, Bangladesh wants to keep open the option of whether the vaccine can be collected from any source.
“I am not waiting for that moment. We are already contacting different countries to get vaccinated. I am not prioritizing any particular country. The vaccine will be collected from where the fast and effective vaccine is available.
The third phase of the potential vaccine developed by Synovac Biotech Limited will also be tested in Bangladesh.
Chinese ticker test
Sinovac Biotech Limited of China received approval from the Bangladesh Medical Research Council (BMRC) on July 16 to carry out the third phase of the vaccine in Bangladesh. But due to the government’s delay in making a decision, the matter has been pending for about a month and a half.
“We have decided in principle to allow the trial,” Health Minister Zahid Malek told reporters on Aug. 26, saying that the government had finally given its approval. Only those who come voluntarily will be judged. We have also informed the Chinese ambassador in Dhaka and the Sinovac company ”.
According to the announcement, the experimental application of this vaccine in Bangladesh will be carried out by the International Center for Diarrhea Research ICDDR, B. Initially, there is talk of the experimental application of this vaccine in health workers in the country.
The Synovac Ticker clinical trial will be conducted in Bangladesh in the same way that the third phase trial is being conducted in other countries around the world.
The accepted method in this case is to administer the parent vaccine to a separate group in the trial. Another group will be given a ‘placebo’, which means that even if it is administered into a body as a ticker, no component of the ticker will be there.
None of the trial participants will know whether they have received the parent vaccine or a “placebo.” Both teams will be monitored for six months. If there is any kind of physical problem, they will report it immediately. A team of experts will periodically analyze the effects of the vaccine.
From there, the decision will come: how effective that vaccine is. And this entire trial should be done to ensure the safety of all participants.
The Serum Institute of India expects Indians to receive the Covid-19 vaccine invented by Oxford researchers by this year.
How will the Indian vaccine come?
The third phase of the possible vaccine developed by the University of Oxford and AstraZeneca is being tested in Brazil, the United States, the United Kingdom and India. And the vaccine called Covishield is involved in the testing and production of the best institute in India – IBS.
IBS has already partnered with Oxford and AstraZeneca, the Gates Foundation, and Gavi to produce more than 100 million doses of the vaccine and supply it to countries around the world.
During a recent visit to Bangladesh, Indian Foreign Secretary Harsh Vardhan Sringla discussed the Indian-made vaccine with him. Sringla said Bangladesh would have priority if the vaccines were made in India.
Bangladesh’s Ministry of Foreign Affairs said that Bangladesh is ready to provide any kind of assistance to India in the development of the Covid-19 vaccine, including the trial. Once the vaccine is ready, Bangladesh wants to get it at an affordable price.
Ten days later, on August 26, Beximco Pharmaceuticals Limited, the country’s leading pharmaceutical company, said it had reached an agreement with the Serum Institute of India to supply the vaccine to Bangladesh if it was made in India.
Under the agreement, Beximco Pharmaceuticals will be the “exclusive distributor” of the SIE vaccine in Bangladesh. The amount of vaccine that can be brought in and how much it will cost will be decided after discussion.
A press release issued by Beximco on the same day said it would also ensure that the Bangladeshi government “meets the needs”.
“The government will be offered to preserve the vaccine at a price to be agreed by the government of Bangladesh and the SII,” he said. Beximco Pharmaceuticals Limited will also guarantee the supply of vaccines to the private market in Bangladesh. ”
Two days later, Health Minister Zahid Malek told reporters: “We have already received the Oxford vaccine in Bangladesh. This is being prepared by the best company in India and Beximco will take the necessary steps to deliver it to Bangladesh along with this best The issue has also been officially discussed. “
The minister also said that a letter was being sent through the Foreign Ministry to obtain the Russian-made ‘Sputnik’ vaccine.
However, many experts in Europe and America are concerned about the safety of the vaccine for humans when it goes into production without a third stage test.
When asked about this, Health Minister Zahid Malek told bdnews24.com: “What we achieve sooner and more effectively will be our priority. Absolutely not all vaccines are available, the interests of the people of our country comes first. We will go where people are healthy. “
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