A team from the Broad Institute in Massachusetts reported that a single case appears to be responsible for 245,000 other final cases.
One was particularly bad. A mutating virus – a small genetic mutation they identified as C2416T – was apparently carried to the conference by a single person, and 245,000 people were infected. Another viral strain with a mutation called G26233T ended in 88,000 people.
“An introduction had a distinctive effect on post-introduction transmission as it spread to a very mobile population as early as possible, before many public health precautions were taken,” the team wrote.
“While Massachusetts contributed to the initial spread concerning this conference, Florida had the largest share of the case overall.”
It is difficult to document a supersparing event. Researchers must show that people were infected and in contact with each other. When thousands or hundreds of thousands of people are involved, it is almost impossible.
But genetic fingerprinting makes it possible. The Broad team used viruses databases to detect these individual mutations, known as single nucleotide polymorphisms or SNPs (pronounced “snip”).
“We think this is an important precautionary story of the downstream effects of superspeeding, which is more consistent with the arrival of the holiday season, and the introduction of vaccines that may not reduce transmission,” McKinsey told CNN.
Only about 200 people attended the Biogen Conference in Boston in late February, which took place before widespread epidemic precautions were taken. The company then teamed up with researchers to help study what happened.
C2416T Transformation U.S. May be generated out. The researchers examined a global database of coronavirus samples and found it in two French patients diagnosed on 29 February. U.S. In, it was only seen in patients associated with the conference before March.
“Taken together, the low-level community transmission of the CA 2416T in Europe strongly suggests that after Alley (transformation) arrived in Boston in 2020 with an introduction, which was expanded by the conference,” the researchers wrote.
In other words, one person delivered this particular version of the virus to Boston and it spread to the conference.
Another viral fingerprint, the G26233T, appears to have been born from the conference, the researchers said. “Before the cases involving the convention, it did not appear in any of the public genome databases,” he wrote.
These special fingerprints make it easy to track the spread of the virus from a single event.
The C2416T mutation spread rapidly in the Boston area, showing between 30% and 46% of the samples taken in the four county Boston area in early spring.
“By November 1, 2020, the virus containing C2424 T could be found in 29 states.”
“As a company rooted in science, we understand the value of data from the first wave of epidemics in the Boston area, and we hope that the information gained from these data will help to continue a better understanding of its transmission.” Stated in a statement.
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