According to a study published Monday in the Mayo Clinic, children and toddlers who received a single dose of antibiotics had asthma, eczema, hay fever, food allergies, celiac disease, weight and obesity problems and increased attention deficit hyperactivity in childhood. Proceedings.
Multiple antibiotic treatments under the age of two were associated with a child with multiple conditions that differed due to the child’s gender, age, type of medication, dose, and number of doses.
“We want to emphasize that this study does not show the cause of these conditions, but the connection,” said Nathan Labrasure, senior study author and researcher at the Mayo Clinic Center for Aging. “These findings provide an opportunity to target future research to determine more reliable and safe approaches to time, dosing and types of antibiotics for children in this age group.”
“Among the children who received one or two prescriptions, only girls were at risk of developing blindness and celiac disease.” “In contrast, receiving three to four prescriptions is associated with asthma, atopic dermatitis and weight gain in both sexes, ADHD and celiac disease in girls and obesity in boys.”
The study found that children of both sexes who received five or more prescriptions had a “significantly higher risk of developing asthma, allergic rhinitis, overweight, obesity and ADHD.” Girls were at higher risk of celiac disease.
The study found penicillin, one of the most commonly prescribed antibiotics, “associated with asthma and weight gain in both sexes, celiac disease and ADHD in girls, and the risk of obesity in boys, while they reduce the risk of autism in girls.”
Other commonly prescribed antibiotics, cephalosporins, in most situations, were associated with a higher risk and “uniquely, autism and food allergies,” the study found.
Microbiome connection?
Why would antibiotics have such an effect – if indeed future studies would repeat the connection?
This is probably due to the breakdown of bacteria in a child’s gut, which is essential for the proper development of the immune system, neural development, body composition and metabolism, Labraser and his team said.
Antibiotics do not distinguish between “good” and “bad” bacteria in the digestive tract, they kill them all and leave them without gut. Proper microbiome distribution. We need some bacteria to absorb nutrients, break down food in the gut and protect the entire digestive system from pathogens.
The explosion of research about our microbiome has shown that it can play a role in everything from how we respond to chemotherapy to the chemistry of the brain and the immune response.
“When antibiotics were first developed and deployed, the overwhelming consideration was the control of pathogens. We now understand that their widespread use on microbiome has a significant collateral effect, which may be of particular importance in developing children.”
The author of “Baby and Child Health” and the American Academy of Pediatrics, pediatrician Dr. “Reducing antibiotic use may be helpful in preventing antibiotic resistance, but may play a role in the accumulation of microbiome, depending on the study,” said Jennifer Shu. “Heading home with your newborn.” Shu was not involved in the study.
“Of course, more studies will be needed to support or refute these findings,” he said, as it is unclear if the study’s findings are “correlated or functional.”
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