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Remdesivir has been identified as a potentially effective treatment for severe cases of Covid-19 and is widely used to treat hospitalized people.
The now published recommendation, according to a WHO statement, is based on a new evidence review, which compares the effects of various drugs against Covid-19, and includes data from four international trials involving more than 7,000 people hospitalized with Covid- 19.
After a comprehensive review of the evidence, the expert panel concluded that remdesivir “does not have a significant effect on mortality or other important patient outcomes, such as need for ventilation or rate of improvement.”the statement says.
The experts emphasized that there is no evidence that remdesivir has any benefit for patients. And they advise against its use, either because of the possibility of side effects or because of its administration (intravenous).
Remdesivir and interferon ineffective
On October 16, the WHO released the results of a trial it sponsored according to which remedial drugs and interferon were not effective in fighting Covid-19.
That same day, at a press conference, WHO Director General Tedros Adhanom Ghebreyesus said that so far the corticosteroid dexamethasone was the only therapy that had proven effective against Covid-19 in patients with serious illnesses.
Tedros Adhanom Ghebreyesus said WHO officials noted that interim trials showed that remdesivir and interferon “have little or no effect in preventing death from Covid-19 or reducing hospitalization time.” And he noted that it was the largest trial ever conducted, involving 13,000 people from 500 hospitals in 30 countries.
with agencies
