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“The neurological symptoms are becoming more and more terrifying,” Alysson Muotri, a neuroscientist at the University of California, told the acclaimed journal Nature.
The list of coronavirus effects on the brain is getting longer, from less severe cognitive conditions to, among other things, strokes, blood clots, and memory loss.
Also in mildly ill people
A study published in July, led by neurologist Michael Zandi of University College London, took a closer look at 43 patients with neurological complications after COVID-19.
Of the patients studied, some of them had experienced only mild respiratory symptoms, but they were still among the most severely affected neurologically.
“That the brain was attacked was his main disease,” Zandi told Nature.
Also at the Oslo University Hospital (OUS), they have seen that some of the patients struggle with cognitive and psychological symptoms, even though they have not been seriously ill from the infection itself.
– For most people, this works fine, but some suffer from longer-lasting ailments, says neurologist and chief physician Anne Hege Aamodt at Rikshospitalet to Dagbladet.
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Neurological pain
Aamodt says that covid-19 can cause a number of neurological symptoms such as headaches, dizziness, taste disturbances, impaired consciousness, effects on peripheral nerves and, in rare cases, other effects on the brain, such as an accident. cerebrovascular.
– Delirium is generally common in intensive care patients and has been shown to be very common in patients with a crown. Especially for the elderly, she says.
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Neurological ailments have been shown to follow patients for a long time, and for some, the ailments are very painful.
– Some people suffer from headaches and pain in the arms, legs and face. Also, many people take a long time to get back in shape and have reduced stamina. Some are completely out of commission due to pain, explains Aamodt.
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Can hit anyone
The following neurological disorders can affect people of all ages, and according to Aamodt, younger people have developed such pain as well.
– Many things happen like this for months, and it is a real annoyance for many, although most of them overcome it well. In other words, there are many reasons to follow the infection control rules of health authorities. This is not like a normal flu, he emphasizes.
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For most people with neurological disorders related to COVID-19, it appears to be an indirect effect, the result of a strong immune reaction against the virus, Aamodt says.
– The olfactory nerve appears to be exposed to a direct influence on the virus, but only in very rare cases has a direct influence on the brain or other nerve cells been revealed.
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To investigate possible neurological tendon damage after the coronavirus, Aamodt is now leading a national study in which neurology departments across the country will examine the extent of neurological, neuropsychological and neuropsychiatric problems after COVID-19.
– This is a national collaborative project between neurologists, neuropsychologists and psychiatrists. Over the next year, 150 former corona patients are invited for follow-up exams six months and one year after suffering from the disease.
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Fewer survived
Aamodt is also one of the researchers behind a recently published pilot study. Here they studied neurofilaments, a marker that nerve cells are damaged and that the brain is affected.
In the study, blood samples were taken from 47 corona patients who were hospitalized. 21 percent of them were admitted to the intensive care unit, while 13 percent of them died during their stay in the hospital.
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“Those who had a high concentration of neurofilaments in their blood on admission had a higher risk of becoming seriously ill or dying during their hospital stay,” says Aamodt.
Other studies have similarly found that those with severe illnesses had elevated levels of neurofilaments, according to Aamodt.
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– This needs to be investigated in several studies and, among other things, was studied in the Norwegian study, so it is not currently used in clinical practice. But methods that facilitate monitoring of the brain of critically ill patients are useful and can contribute to the progress of the health service.
– Getting better monitoring of the brain is something that concerns us in all contexts. You can then better manage treatment and rehabilitation can also be optimized when you know that the patient has a brain effect.
– I’m not sure if he would survive.
I was afraid of several stroke patients
When the pandemic reached Norway, Chief Physician Hege Ihle-Hansen of the stroke section at Oslo University Hospital says there were fears that the virus could lead to more strokes. Especially in patients at risk of stroke and other vascular diseases.
– But we’ve had two simultaneous stroke and coronavirus patients, so it can be completely random, he tells Dagbladet.
– We have not learned anything in this first round that allows us to say something more about it.
