Mysterious post-covid syndrome seems to affect children even worse than we thought


After contracting and beating a coronavirus infection, the body needs time to rest to regain its health and strength. Sadly, for some kids, that doesn’t happen.

A mysterious, new disease called Multisystem Inflammatory Syndrome in Children (also known as MIS-C, and Pediatric Multisystem Inflammatory Syndrome or PIMS) has affected hundreds of children around the world since it was first discovered earlier this year.

This condition, thought to be somehow linked to COVID-19, can occur in children even after a very mild coronavirus infection. But a light case of coronavirus is no guarantee that subsequent MIS-C cases are not very serious, and sometimes not even fatal.

“Children didn’t need to exhibit excellent upper respiratory symptoms of COVID-19 to develop MIS-C, which is awesome,” says Alvaro Morera, a neonatologist at the University of Texas Health Sciences Center in San Antonio.

“Babies may have no symptoms, no one will know they have the disease, and after a few weeks, they may develop this exaggerated inflammation in the body.”

In a comprehensive new review of medical research at MIS-C, from this year, Morera and his team found a study of about ob0 observations, involving a total of 62,628 pediatric patients who developed the syndrome.

MIS-C is characterized by severe inflammation in many parts of the body, including the heart, lungs, kidneys, brain, skin, eyes, and more. These symptoms are similar to two other conditions – Kawasaki disease and toxic shock syndrome – but the overall inflammation rate and prevalence in MIS-C is worse, says Morera.

“It can be fatal because it affects multiple organ systems,” Morera says. “Whether it’s the heart and lungs, the gastrointestinal system or the neurologic system, it has so many different faces that initially it was difficult for clinicians to understand.”

Now, many months after the Kovid-1p epidemic, we are getting a clearer picture of what MIS-C looks like, however, we still don’t understand much about the syndrome – as well as the prospects for long-term recovery. Be for experienced young people.

Of the 662 cases known worldwide in the new review, 71 percent of children were admitted for intensive care, and the average length of hospital stay was eight days.

In each case, patients showed fever, and most also presented with abdominal pain or diarrhea (73.7 percent of cases) and cases of lumbar (68.3 percent). Conjunctivitis and rash were also common.

Sadly, 11 of the study’s children died. While this observation appears to have a lower mortality rate for children with MIS-C (approximately 1.7 percent of all child patients in this study), the researchers said the figure is actually much higher than the 9.09 percent mortality rate seen in children. With COVID-19.

In cases where children have recovered, however, there is much concern about what MIS-C can do to their heart. In the study, about 90 percent of children had an echocardiogram (EKG) test, and more than half (54 percent) of the returning results showed abnormalities.

These abnormalities include coronary artery rupture, depressed ejection fraction (decrease in the heart’s ability to pump oxygenated blood to body tissues), and in about 10 percent of patients, coronary artery aneurysms, which can put them at greater risk. Future cardiac events.

“These are children who need significant observation and need to be followed up with multiple ultrasounds to see if this is bringing a solution or if this is something they will have left for the rest of their lives,” Morera says.

“It is disastrous for a parent who previously had a healthy child and then he / she is in a very small percentage of MIS-C developed individuals after Kovid-19 infection.”

The authors note several limitations of their study and point out that they may have missed some studies despite MIS-C’s extensive research.

Although we do not yet know much about MIS-C, the picture that is beginning to emerge is one that we should take very seriously: the disease associated with covid-1, which is experienced by many children. Is worse. They have faced COVID-19.

In rare cases where MIS-C is suspected, first aid is a crucial action that can save the lives of children.

The authors write in their study, “Children will show signs and symptoms of MIS-C three to four weeks after COVID-19 infection and progress rapidly to many traumas and heart failure.”

“Families should seek immediate medical attention as children with this condition disintegrate rapidly and most children need management in an intensive care unit. Agents. “

These findings are reported EClinicalMedicine.

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