Marijuana use during pregnancy is linked to autism in infants, study says


“Women who used cannabis during pregnancy were 1.5 times more likely to have a child with autism,” said the study’s author. Darine El-Chaâr, a maternal specialty specialist and clinical researcher at Ottawa Hospital Research Institute in Canada.

“These are not reassuring findings. We strongly discourage use of cannabis during pregnancy and breastfeeding,” she said.

“On that basis, “I’m not too surprised by these findings,” said El-Chaâr. Fetal brain development occurs at all gestational ages. “

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The study, published Monday in the journal Nature, looked at data from each birth in Ontario, Canada, between 2007 and 2012, before recreational marijuana was legalized in Canada in 2017. Of the half a million women in that data pool, researchers then examined the study to 2,200 women who said they only used marijuana during pregnancy, without mixing it with tobacco, alcohol or opioids.

The study did not capture the amount and type of marijuana that women used during pregnancy. The study also did not know when during pregnancy or how often women used it. And although the study could only show association, not cause and effect, researchers said they did their best to eliminate confusing factors.

Weed use during growth of pregnancy

As weeds become legalized and socially acceptable, health care researchers are making moms-to-be think it is good to use to treat morning sickness or recreational use, despite the lack of long-term impact research on a fetus.

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Women also chose to use marijuana to prevent medications they felt were more harmful to their baby, such as anti-malice pills, anti-psychotic medications and opioids, a small study of pregnant women by Washington State researchers University found.

Pain management, El-Chaâr said she hears from expectant mothers, is the most common reason for using marijuana.

“It helps in various circumstances they may have like for nausea and vomiting in pregnancy,” El-Chaâr said. “Some people (said) they use (it) for sleep or for stress reduction. Still others use it recreationally; it’s just part of their routine.”

Marijuana use by pregnant women has grown in recent decades in the United States. An analysis last year of more than 450,000 pregnant American women ages 12 to 44 by the National Institute on Drug Abuse found that cannabis use more than doubled between 2002 and 2017.
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The vast majority of marijuana use was in the first three months of pregnancy, the study found, and was primarily recreational rather than medical.

However, the first trimester can be one of the most sensitive times for developing a fetus’ brain, when it is most susceptible to damage, El-Chaâr said. Studies have found recipients of cannabis in the brains of animals as early as five and six weeks of gestational age, she said.

“You can hypothesize that if there are cannabinoid receptors and the baby’s brain is exposed, it could (have) an effect on brain development,” she said.

What to do

Every woman who uses marijuana and discovers she is pregnant should discuss her use immediately with her doctors, experts say. However, many young women are not honest, studies have shown. One study of women aged 24 and younger found that they were about twice as likely to screen positively for marijuana use as they stated in self-reports.

The self-reported prevalence of marijuana use during pregnancy varies from 2% to 5% in most studies, according to the American College of Obstetricians and Gynecologists.

“Pregnant women as well as women considering pregnancy should be encouraged to stop using marijuana for medicinal purposes in favor of an alternative therapy where there is better pregnancy-specific safety data,” ACOG states in its recommendations.

“There is insufficient data to evaluate the effects of marijuana use on infants during lactation and breastfeeding, and in the absence of such data, marijuana use is discouraged.”

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