In Lithuania, most adverse reactions to coronavirus vaccines were reported by women.

Symptoms of adverse reactions. – Similary

Andrulionis, who presented adverse reactions to coronavirus vaccines, said most of the complaints were mild. He also added that women made more complaints.

According to the IWT director, all reports of adverse reactions remain similar: pain, swelling, redness at the injection site, arm pain, headache, rash, chills, fever. After one or several days, these disorders passed.

8 deaths were reported

8 post-vaccination deaths have also been reported, but they are not related to the coronavirus vaccine.

“Deaths of the elderly and elderly have been reported. The youngest patient is 69 years old, the oldest 91 years old. 5 women, 3 men. Reported from Vilnius, Tauragė, Šiauliai, Panevėžys, Joniškis and Druskininkai. However, in our estimate, all reported deaths were related to the life expectancy of these patients. Some patients were cared for at home with chronic diseases. One case was from a nursing hospital, where a person became ill with COVID-19 and died despite being vaccinated ” said R. Pilvinienė, adding that they were not active people.

Commenting on the adverse reactions to the coronavirus, the specialist said: “Of the reports mentioned, there were several, about 8 cases of fainting that were associated with fever and general malaise. Similar to the previous month, we noticed some unexpected reactions that have not yet been recorded in the Summary of Product Features. Something very new did not come out this month, the unexpected side effects were exactly the same as last month. It is a feeling of numbness in the face, tongue, limbs, or even the whole body. There have also been cases of increased blood pressure and frequent heartbeats. “

One case of facial paralysis has been reported with Vaxzevria. Before that, there was such a reaction to the Moderna vaccine.

Six reports of blood clots

R. Pilvinienė said that six reports of blood clots had been received. It is true that specialist-observed IWT reports were received at a time when vaccination with AstraZeneca had been discontinued due to a possible risk of blood clots and was widely reported in the media. All the reporters were elderly.

“I want to note that the flow of messages was caused by the uproar, which was widely covered in the press. With the distraction, we did not receive any more reports of thromboembolic events. Actually, 6 messages reached us that day. Of these, 3 were reports. of thrombophlebitis, 2 of which were a complication of pulmonary embolism and hospital treatment. 2 reports were of cerebrovascular accidents. But all those reports came, in principle, the day after stopping the vaccination with AstraZeneca “, said the specialist of IWT.

R. Pilvinienė emphasized that these cases of thromboembolism were due more to age than to the vaccine.

Messages have been dropped

R. Pilvinienė noted that most vaccinated people have the Comirnaty vaccine. The largest flow of reports of adverse reactions was recorded in February. At that time, there were many reports of suspected adverse reactions to AstraZeneca. However, there are currently no such reports, although many more people have been vaccinated.

“It’s clear that more people in the priority age group are currently being vaccinated. You see, the highest human flows for all 3 vaccines are vaccinated between the ages of 60 and 89. More adverse reaction reports are received from those groups with increased vaccination coverage, ”said R. Pilvinienė.

According to the expert, most of the reports are from older people vaccinated with AstraZeneca. Comirnaty represents almost 1 notification per 1000 vaccines and AstraZeneca 4 reports per 1000 vaccines.

Although according to R. Pilvinienė the number of vaccinated men is increasing, women are still more active in reporting.

As mentioned, most of the reactions are mild, with the most serious reactions accounting for a small proportion of the reports.

“It’s a bit surprising that the patients themselves are doing more reporting. The reports presented by health professionals constitute a very small part ”, said the specialist.

The most common categories of local disorders and injuries reported after Comirnaty were reported. Second, for the skeletal and connective tissue class. Also for Moderna and AstraZeneca vaccines.

A total of 1742 messages were received

During the three months after vaccination from the start of COVID-19 vaccination (December 27 to March 31), IUDs received 1,742 reports of suspected adverse reactions (IRRs) to the vaccine. The CNS reports represent 0.34 percent of the total number of vaccines (the number of vaccine doses used on March 31 was 494,738).

During this time, the people were vaccinated with three vaccines currently available on the Lithuanian market. The COVID-19 Vaccine Janssen vaccine, whose conditional registration was approved by the European Medicines Agency on March 11, should arrive in Lithuania by the end of April.

In the third month of vaccination, the IUD received 541 reports of suspected adverse reactions (ADRs) in Lithuania related to the use of COVID-19 vaccines. There have been 150 reports of ERC after the Comirnaty administration; There were 63 reports of CKD after administration of the COVID-19 Vaccine Moderna vaccine and 326 notifications of CKD after administration of Vaxzevria. The name of the vaccine was not mentioned in 2 RNA reports.

498 messages are classified as mild to moderate and 43 as severe. Women reported more from the CNS than men, 428 and 111, respectively. The age range for CIS reporters is 19 to 92 years old. The number of notifications received from healthcare professionals is 40 and from patients 493. 8 notifications were received from the Eudravigilance database.

The main reports of people vaccinated with COPD-19 who received IUDs remain similar, including pain, swelling and redness at the injection site, arm pain, chills, headache, rash and fever. The most common of these reactions was mild to moderate and resolved within a few days.

The SCCP recalls that the Summary of Product Characteristics and the package insert for registered COVID-19 vaccines include recommendations and precautions to be followed by healthcare professionals and patients to use the vaccines safely and effectively. As with all medicines, data on vaccine use is constantly monitored. Every COI report for COVID-19 vaccines received by ICD is carefully evaluated and all necessary steps are taken to protect patients.

The IGC notes that GIs related to the vaccine should be notified in cases where a link to the specific vaccine used is suspected, as well as in cases where the causal relationship between the GI drug and the vaccine / vaccine is in doubt. . This should be reported by the healthcare professional or the patient.