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This conclusion was made by a medical team at Columbia University’s Irving Medical Center in New York, one of the hospitals that was flooded with Covid-19 patients in the spring, after reviewing their own reports and collecting them from elsewhere. of the world.
According to doctors, the coronavirus attacks almost all major body systems, directly damaging the organs and causing blood clots, causing the heart to lose a healthy rhythm, the kidneys are unable to filter the blood adequately and the skin rashes severely.
The coronavirus causes headaches, dizziness, stomach and muscle aches, as well as the classic symptoms of respiratory problems: cough and fever.
Scanpix Photo / Coronavirus pandemic
“Doctors must think of Covid-19 as a multifunctional disease. There is a lot of news about the blood clots in the coronavirus, but it is also important to understand that many patients with Covid-19 also suffer from kidney, heart and brain damage, and doctors must treat these diseases along with respiratory diseases, “says the cardiologist Aakriti Gupta. .
Most of the damage to the virus appears to be due to its affinity for a very important receptor called ACE2, a molecular gateway to cells.
The cells that enclose the blood vessels, kidneys, liver ducts, pancreas, intestinal tract, and airways are lined with ACE2 receptors, which the virus can use to infect cells, the Colombian team wrote.
Photo from 123RF.com / Coronavirus Research
Coronavirus infection, according to doctors, also activates the body’s immune system. And part of this “defense response” is the production of inflammatory proteins called cytokines. As a result, this inflammation can damage cells and organs, and the so-called cytokine storm is one of the causes of severe symptoms.
“This virus is really unusual, so it is difficult to see how much it can affect our bodies,” said Mahesh Madhavan, another cardiologist who worked on the report.
Blood clots are caused by several different mechanisms: direct damage to the cells that cover the blood vessels and disorders of the blood’s own clotting mechanisms. The researchers say that a decrease in the amount of oxygen in the blood due to pneumonia can also lead to an increased risk of blood clots.
Clots can cause a stroke or heart attack, or they can travel to the lungs or legs. Clots also obstruct the kidneys and interfere with dialysis procedures, which are especially necessary in critically ill patients.
Photo from 123RF.com/Coronavirus
Patients with diabetes mellitus and coronavirus infection have been shown to have a high risk of developing the strong form of Covid-19 and an increased risk of death.
Coronavirus also directly affects the brain, but most neurological damage is not caused by the infection itself, but by treatment, doctors say.
“COVID-19 patients are usually intubated for two to three weeks, a quarter of whom need ventilators for 30 days or more.
These are very long intubations, so patients need a lot of sedation. Therefore, the hallucinations or other neurological disorders that can occur after that are not a consequence of the virus but of sedation, ”said cardiologist Aakriti Gupta.
The virus acts on the immune system by depleting the T cells that the body normally uses to fight viral infections.
“Lymphopenia, a marker of impaired cellular immunity, is a reported cardiac laboratory finding in 67-90% of patients with COVID-19,” the researchers wrote.
According to them, patients with coronavirus should receive treatment for all these conditions.
But researchers also provide good insights.
Gastrointestinal disorders with coronavirus are not very dangerous, and many effects on the skin, such as rashes and red spots or swollen fingers, also disappear after recovery.
A review of the study, published in the journal Nature Medicine.
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