Dr. Anthony Faucy was on CNN Monday morning, mourning Number of daily positive tests for COVID-19. Of course, this is always called a “case”, which people with a medical background want to tear hair for many reasons. However, it is crucial for the chosen description that you think there are 40,000 new sick people every day. People who may need the kind of state-of-the-art care given to President Trump at People Litter Reed Medical Center.
The idea is ridiculous, misleading and alarming for many reasons. First, quoting “cases” of illness indicates that the person has his or her symptoms. With a significant number of people testing positive for COVID-19, this is not the only case. People who are not and are not sick get positive test results because of the common type of testing method used to detect the virus.
PCR testing cannot detect live viruses. For a virus to infect a person or infect another person, it must be able to replicate. The PCR itself does not measure the ability of the detected material to make additional copies. It is appropriate to use the word content because the PCR test looks for fragments of the virus’s RNA. It does not require a complete RNA strand to return a positive result.
Questions Questions An honest, intelligent reporter d. Fawcett will ask about COVID-19
The CDC knows this, and so does the FDA. This knowledge is why CDC will no longer suggest retrieving recovered patients. The agency acknowledged that the patient would be incapable of transmitting the virus for up to 90 days and infecting. When you add research about T-cell immunity to this mix, it is understandable why there are so many asymmetrical cases.
T cells are immune cells that live in the lymphatic system, and some have a type of “memory”. They identify parts of viral and bacterial invaders and are activated to remove them from the body through complex immunity. Research has shown substantial similarities between COVID-19 and other coronaviruses suggesting that this reaction occurs somewhere between 40% to 60% of the population.
A Swiss biologist, an Emirates professor and former director of the Institute of Immunology at the University of Bern, Dr. Beda m. Stellar Dollar noted that the same virus particles found in the recovered patient would be found in a person with an effective immune response COVID-19 (Load mine):
So if we test the PCR corona on an immune person, it is not the virus that has been detected, but a small fragmented part of the viral genome. The test comes back positive as long as small fragments of the virus remain. True: Even if the infectious virus has been dead for a long time, a corona test can return positive, because the PCR method is sufficient to amplify even a small portion of the viral genetic material [to be detected].
Reporting on The New York Times This observation echoed. According to a study conducted on positive samples in New York, Massachusetts and Nevada, 90% of the tests had very little viral debris in the sample, indicating that infection and transition were not possible:
In three sets of data that included cycle thresholds prepared by officials in Massachusetts, New York and Nevada, a review by the Times found that 90 percent of people had barely tested for a virus.
As of Thursday, 45,604 new coronavirus cases had been reported in the United States, according to a database maintained by the Times. If contagious rates are applied nationwide in Massachusetts and New York, perhaps only .00 of those people will need to be isolated and submitted for contact tracing.
In the article, Harvard T.H. Dr. Chan School Public Health Epidemiologist. Michael Meena explained the problem:
Dr. “We use one type of data for everything, and that’s just plus or minus -” Meena said. Meena said. “We’re using it for clinical diagnostics, for public health, for policy making.”
The New York Times does accidental journalism on the COVID-19 test
The PCR test detects the virus by amplifying the RNA it detects. Each amplification is called a cycle. The test uses more cycles, the RNA of the virus. No pieces are more likely to be found. In the United States, most labs go through 40 cycles, according to Times. Expert interviewers said that the number of cycles is unnecessarily high:
“Tests with a threshold can detect not only live viruses, but also genetic fragments, there is no risk of infection,” said Dor Meena. Meena said.
Riverside University of California virologist Juliet Morrison, 35. Any examination with a cycle threshold above 35 is highly sensitive. “I’m shocked that people think 40 can represent the positive.”
A more reasonable cutoff would be 30 to 35, he added. Dr. Meena said they would put the figure at 30 or less. Those changes mean the amount of genetic material in the patient’s sample should be 100 times to 1000 times the current standard to give a positive result for testing – at least, it is workable.
So, looking for a hypersensitive test “case”, Dr. F. is tying the key to steam. Taiwan, which has been praised for its response to the virus, uses a cycle threshold of less than 32 years to diagnose patients who are sick and potentially infected. Without a doubt, this allows them to do more effective contact tracing and mitigation. They are targeting the contacts of people who are likely to be infected. The Oxford study found more than 30 cycle threshold non-infectious cases.
Large scale study in India gives more insight. While it is not clear which test was used, PCR is the most common. In this study, 75,965. Contacts of individuals were traced, in which 75750,071 contacts could be verified. It found that the proportion of infected 8% in new cases is as high as 60%. Data on the cycle thresholds of those who have been infected with the virus will help set reasonable limits for detecting infectious cases.
This Los Angeles Times It refers to the 8% who infected many people as “super spreaders” because it’s a scary word. It is more plausible to assume that those individuals had a viral load that is capable and capable of producing large amounts of viral doses to infect others. Viral doses in contact with COVID-19 are hypothesized to determine the risk for illness and severity.
Answers COVID-19 We will all demand now
The FDA, which approves COVID-19 tests, and the CDC, which provides clinical guidance, need to immediately consider the sensitivity of the test. The FDA Appropriate cycle thresholds need to be set for testing laboratories, and labs should take note of the number of cycles taken to detect the virus on all test results. The CDC needs to provide clinical guidance for providers who set a reasonable cycle threshold for positive testing that requires contact tracing.
If Taiwan has successfully used 32 as a potential for transmission, and domestic health experts agree that 30-35 is more than enough, why do our labs regularly do 40? It certainly speeds up the number of positive tests, giving tin-pot dictatorships in statehouses across the country that you can be licked.
You can make a significant bet that the agencies will consider this issue after the inauguration of President Biden. Magically, without any real intervention, the number of “cases” will decrease simply because our agencies will issue rational guidance. The information they need to do this is available today. A reduction of only 35 in the research findings would make contact tracing and mitigation more effective.
Despite extensive reports of this issue, this has not been taken into account, it is unforgivable. And the longer it continues to get its hands on the number of “cases” on television, it looks more political.
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