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Real Madrid fell to a shocking second Champions League defeat for Shakhtar Donetsk to slide to third position in Group B.
Real Madrid were looking to rematch their surprise 3-2 home defeat in October, but second-half goals from Dentinho and Solomon surprised them again.
Real have never failed to qualify for the round of 16 of a Champions League campaign in 24 attempts, but they have work to do now, while Shakhtar have a real chance of reaching the round of 16 after climbing to the second place.
Borussia Monchengladbach stay on top despite a 3-2 loss at home for Inter de Milan, who also kept alive their hopes of making progress on what promises to be an exciting final day.
Matteo Darmian and two from Romelu Lukaku gave Inter the victory, with goals from Gladbach from Alassane Plea.
Liverpool, which had Caomihin Kelleher of the Republic of Ireland in goal, secured their qualification and first place in Group D thanks to a goal by Curtis Jones in a 1-0 win over Ajax.
A howl from Ajax goalkeeper Andre Onana gifted young Jones with his first Champions League goal at Anfield.
Atalanta are seconds after Cristian Romero annulled Alexander Scholz’s first match in a 1-1 draw with FC Midtjylland.
A late Thomas Muller penalty won Bayern Munich a 1-1 draw in Atletico Madrid, which means the Spanish team must avoid defeat at Red Bull Salzburg in their last group match to progress.
Joao Félix had put Atlético ahead midway through the first half against a Bayern largely in the second row, who had already qualified.
At the other end of Group A, Mergim Berisha scored twice as many Salzburg hit Lokomotiv Moscow 3-1.
Manchester city won Group C despite being tied scoreless by Porto, which have also ended, while two penalties to Dimitri Payet gave Marseilles a 2-1 win against Olympiacos.
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