After months of uncertain speculation, researchers have reported their strongest evidence that patients with coronavirus have a more intense, immune response if exposed a second time.
These new findings suggest that SARS-CoV-2 antibodies may survive more than six months of initial infection, and promote a more effective anti-viral response than they did not catch the coronavirus. It may explain why the rescheduling is so low.
After months of uncertain speculation, researchers have reported their strongest evidence yet that patients receiving coronavirus have a stronger, immune response if exposed a second time.
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“That’s very good news,” said Michelle Nussenzweig, head of molecular immunology at Rockefeller University in Manhattan and senior author of a previously published study on the open-source research site Biroxiv. “The expectation is that people should react strongly to the antibody and resist infection in a large number of cases,” he told the Guardian.
Scientists call this the “memory” of the immune system, backed by its T- and B-cell anti-viral forces. The two types of immune cells work together in their efforts to produce antibodies in the blood, and then suppress and kill SARS-Covi-2, the new coronavirus that causes Covid-19. More specifically, T-cells lead the invasion against the virus by destroying infected cells, while B-cells analyze the virus to produce antibodies, which collect and trap the invaders. Finally, macrophages, yet another serious immune cell, will then clean up the mess.
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Once embedded, the immune system stores “memory” T- and B-cells, which have developed special defense against coronavirus. If the Covid-19 should return, they will be allowed to fight the virus again.
The Rufffeller study included 87 patients with Covid-1, who were tested for antibodies a month later and again in about six months, until their survival level was only 20% compared to the peak level of the patients. However, researchers are less concerned with the overall concentration of residual antibodies as they have been shown to be particularly strong in combating the disease a second time.
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At the same time, the UK Coronavirus Immunology Consortium recently posted an immunological study of its own. Her study of 100 people who had previously tested positive for coronavirus showed a “strong T-cell response” beyond six months.
Read a report on the consortium’s website that, six months after SARS-CoV-2 infection, T-cell responses were present in all individuals. “Strong cellular memory against viruses lasts for at least six months.”
Notably, the “size of the T-cell response” was 0% higher in people who tested positive, but were symptomatic, compared to those who did not experience symptoms.
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“The lesson at home is that people who get infected, after six months … memory responses with antibodies that can neutralize the virus and do it very well,” said Newsenzweig. “We don’t know how long any security will last, but it will be really long. It could be years. “
This article appears in the original New York Post.
