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China CDC responds to positive environmental samples from new corona vaccination units
Viral nucleic acid is derived from inactivity of the vaccine and cannot be transmitted
Recently, some provinces tested positive for the new coronavirus in environmental samples collected and analyzed by the new coronavirus vaccination unit.
To this end, the Chinese Center for Disease Control and Prevention recently issued the “Notice on the Issuance of Technical Recommendations for Monitoring Environmental Samples from New Coronary Vaccination Units”, stating that it was preliminarily determined that viral nucleic acid In the new vaccination environment corona comes from the vaccine vial. Since the viral nucleic acid in the inactivated vaccine has no activity, it is not infectious.
The Institute of Viral Diseases of the Chinese Center for Disease Control and Prevention conducted nucleic acid tests on environmental samples from COVID-19 vaccination units collected in some provinces. The results showed that the desks, walls, door handles and corridors of the vaccination units (injection room, observation room, external corridor, etc.) Environmental samples are positive for the nucleic acid of the new coronavirus.
At the same time, the entire genome of the new coronavirus was sequenced in the positive environmental samples and the residual fluid in the vaccine bottle. The results showed that the virus genome sequence in the environmental samples was consistent with the vaccine strain in the tested vaccine vial, and there was a significant difference in the composition of the genome variant sites of the currently circulating strains. . It is preliminarily determined that the viral nucleic acid in the new corona vaccination environment comes from the vaccine fluid.
The novel coronavirus-inactivated vaccine virus is understood to have lost its infectivity and pathogenicity, but still retains relatively complete viral nucleic acid fragments. During the vaccination process, opening the vaccine vial, withdrawing the vaccine solution, exhausting the syringe, the liquid residue in the syringe or the vaccine vial after vaccination, etc., can contaminate the vaccination table , the wall, the door handle and the corridor of the vaccination site in the form of liquid or aerosol., The surface of objects such as the clothing of vaccinators and recipients, and can spread a long distance, causing acid contamination nucleic in the injection room, observation room, outside corridor, other departments near the vaccination clinic and the restrooms. Due to the high sensitivity of polymerase chain reaction (PCR) detection, if nucleic acid fragments are sampled before they degrade, the results of the nucleic acid test are likely to be positive.
Some provinces tested positive for the vaccine strain virus nucleic acid in the environment of the inoculation unit and at the same time performed a nucleic acid test with nasopharyngeal swab on staff, and the result was negative. Although there are no reports of a positive nucleic acid test on nasopharyngeal swabs caused by aerosols caused by inhalation of the vaccine fluid, research attention and evaluation is still needed.
The Chinese Center for Disease Control and Prevention stated that since the vaccination work of the new crown of each vaccination unit will continue for a period of time, the risk of vaccination sites being contaminated with nucleic acid from the shot is high. Routine monitoring of the vaccination environment will interfere with epidemic monitoring and early warning, so it is not recommended to routinely perform environmental sample collection and nucleic acid testing for the inoculation unit. If surveillance has been conducted and found to be positive, it is recommended to use genome sequencing of the virus to determine if the nucleic acid is a vaccine strain.
To organize vaccination and disinfect the environment, the China Centers for Disease Control and Prevention pointed out that vaccination personnel should take appropriate protective measures, such as wearing masks, isolation gowns, work hats, gloves, etc., and take off their individuals after the vaccination is finished. Protective clothing and treat as medical waste, wash your hands before vaccination or use disinfectant to wash your hands to disinfect, change a new mask when you leave the room and do not bring personal belongings to the vaccination room.
The environment of the inoculation unit should also be kept clean, ventilation should be strengthened, and routine cleaning and disinfection should be performed in accordance with regulations. When the nucleic acid of the vaccine strain is positive in environmental samples, no additional large-scale killing measures are required. Strengthen the medical waste management of the new corona vaccination unit, use double-layer garbage bags for packaging and tighten the seal to prevent the nucleic acid of the vaccine strain from contaminating the environment outside the inoculation unit through of medical waste, etc. (Reporter Wu Jiajia)
【Correction error】
【Editor-in-charge: Liang Haiyan】
