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March 26, 2021 / Bio Valley BIOON / — As people pay increasing attention to the mutant strain COVID-19 and its influence on the protective effect of the COVID-19 vaccine, researchers have proposed a method to verify vaccination against SARS- COV-2 infection in people with COVID-19 vaccine.
Genomic analysis of these so-called “mutant” SARS-CoV-2 infections in COVID vaccine trials is a key tool for identifying related viral mutations that affect vaccine protection and predicting how vaccination affects virus evolution.
(Image source: www.pixabay.com)
Dr. Morgane Rolland, director of viral genetics for the Walter Reed Army Research Institute’s HIV Military Research Program, among others, conducted a recent study, the results of which were published in the journal Plos Pathogen.
Rolland explained: “No vaccine is 100% effective. Therefore, even in clinical trials currently promoting a highly effective COVID-19 vaccine, some trial volunteers who received the vaccine have found mutant infections.” Rolland explained: “By comparing the genetic characteristics of the virus that infects the population vaccinated with the virus in the placebo group, it can help to identify which mutants are evading the vaccine-induced immune response and provide a basis for improving the COVID vaccine. -19 “.
Screening analysis allows scientists to understand the evolutionary pattern of the virus, which will be the key to inferring how SARS-CoV-2 adapts to widely used vaccines and predicting how the evolution of the virus will ultimately affect the efficacy of the virus. vaccine. The author noted that the SARS-CoV-2 mutation is relatively slow, meaning the current vaccine is unlikely to be phased out anytime soon, but we still need to be vigilant.
Rolland said: “The emergence of mutant viruses in the last two months indicates that we must improve the next generation of vaccines as soon as possible. Detection and analysis of samples obtained through vaccine trials is an effective way to determine how vaccines should be designed. . in the future “. (Bioon. Com)
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