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- Rachel Schraer
- BBC Health Reporter
Image source,Reuters
Local governments have approved a variety of new vaccines against coronary pneumonia around the world.
In general, it takes several weeks for the new corona pneumonia vaccine to provide complete protection to a person. Some UK hospitals are looking into injecting new corona virus antibodies for some people who need emergency protection to test whether this can make people develop faster against this virus. Immunity.
So far, the researchers have injected antibodies into 10 test subjects and had close contact with people diagnosed with a new coronary pneumonia in the eight days before the antibody injection.
If the trial is successful, the researchers hope this can provide quick protection for some people who have not been vaccinated or cannot be vaccinated.
Instant protection
The trial was conducted at the NHS Trust at University College London Hospitals to investigate whether injections of two different antibodies can prevent people who have been exposed to the virus from getting sick, or at least reduce their condition.
Researchers estimate that this monoclonal antibody therapy developed by AstraZeneca Pharmaceuticals can immediately neutralize the virus and provide continuous protection for up to one year. If medical staff, hospital patients, and nursing home residents have been exposed to known cases of new coronary heart disease, they can use this method to reduce their chances of getting sick.
This therapy can be provided by general practitioners to people with health defects and can prevent one or two cases from developing into large-scale outbreaks in student dormitories and other settings.
The research team led by Dr Catherine Houlihan, a virologist at University College London National Health Service Trust Fund Hospital, expects to recruit 1,000 volunteers. They hope to recruit targets in communities where the virus may have appeared, including hospitals and student residences.
Those who want to participate must show that they have close contacts who have tested positive.
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Dr. Houlihan said the vaccine works by “donating” antibodies, “skipping the stage where your body makes antibodies.”
“We know that this combination of antibodies can neutralize the virus, so we hope to find that through injection, this treatment can immediately protect people who have been exposed to the new coronavirus.”
He explained that similar technologies have been used to treat or prevent rabies, or to protect pregnant women from chickenpox.
Injection before exposure to the virus.
The National Health Service Trust Fund Hospital at University College London is also conducting another trial to see if this antibody treatment can be used before a person is exposed to the novel coronavirus to prevent infection. This is especially helpful for people who are immunocompromised or who are receiving immunosuppressive treatment (such as chemotherapy).
Dr. Nicky Longley (Nicky Longley), infectious diseases consultant, is conducting tests of this type in cancer and AIDS patients, said that these diseases “may affect the ability of your immune system to respond to vaccines.”
“We want to reassure those who cannot protect themselves with vaccines. Antibody therapy can protect them too.”
Dr. Houlihan confirmed that this method can also be used to protect vulnerable people as an interim measure before vaccination. But he said it is not recommended as a substitute for vaccines and that the cost of antibody therapy can be much higher, costing several hundred pounds per dose.
In addition to University College London Hospital, this antibody therapy will also be tested at multiple locations in the United States, Wakefield, Manchester, Southampton, and Hull. But only London began to recruit crowds. Tests using antibodies before and after exposure to the new coronavirus are expected to announce the first batch of research results in the spring.
