[ad_1]
Guangdong Province Disease Control Statement: Guangdong Province Has Discovered a B.1.1.7 Mutant from a Confirmed Case of New Coronary Pneumonia Imported from the UK
Golden Goat 2021-01-03
The case is a British immigrant under closed circuit management, male, 18 years old, Chinese national and international student.
Text / Yangcheng Evening News All Media Reporter Yu Yanhong, Guangdong Disease Control Correspondent
The Guangdong Provincial Center for Disease Control and Prevention launched its official website on January 3, 2021. On January 2, the Guangdong Provincial Center for Disease Control and Prevention found a B.1.1.7 mutant in a sample throat swab from a confirmed case of new coronary pneumonia imported from the UK. The genetic sequence of the mutant virus reported in the UK is very similar.
After the UK reported the variant strain of the novel coronavirus, the Guangdong Provincial Center for Disease Control and Prevention strengthened the analysis of the novel coronavirus gene sequencing of imported cases abroad and conducted a retrospective review of the samples of confirmed cases and asymptomatic infections imported from our province since September last year. Gene sequencing analysis. On January 2, 2021, the Guangdong Provincial Center for Disease Control and Prevention found a B.1.1.7 mutant in a throat swab sample from a confirmed case of novel coronary pneumonia imported to the UK, which is very similar to the genetic sequence of the mutant virus recently reported in the UK.
The case is a British immigrant under closed circuit management, male, 18 years old, Chinese national and international student. It entered Guangzhou from the UK on December 4, 2020, and tested negative for the novel coronavirus nucleic acid upon entry. On December 18, the quarantine site tested positive for the novel coronavirus nucleic acid and was sent to Guangzhou Eighth People’s Hospital for isolation and treatment. The confirmed case was diagnosed and the clinical type was mild. He is still in the centralized medical isolation point of Guangzhou Eighth People’s Hospital. Perform a medical observation after discharge.
On December 27, 2020, the Guangdong Provincial Center for Disease Control and Prevention conducted a genome sequencing analysis on throat swab samples collected by Guangzhou City Eighth People’s Hospital, which initially suggested that it was a mutant B.1.1.7. After another high-throughput sequencing review on January 2, the results showed that the virus gene sequence in the case sample belonged to subtype B.1.1.7. The virus genome sequence contains 13 specific amino acid mutation sites of the mutant strain branch of subtype B.1.1.7, including the S protein N501Y, which has a potentially important impact on the infectivity of the virus, the P681H mutation and protein S related to the immune escape of the virus. Deletion mutation 69-70.
According to the current situation, this mutant strain B.1.1.7 is more transmissible, but the patient’s symptoms, the rate of severe disease, and the fatality rate have remained practically unchanged. Currently developed vaccines remain effective and most of the diagnostic test reagents are still effective. The public should not panic.
The Guangdong Provincial Center for Disease Control and Prevention stated that it will continue to strengthen gene sequencing analysis and monitoring of mutant strains, further implement epidemic prevention and control in designated treatment hospitals and isolation sites, and will continue to implement health monitoring and nucleic acid testing for workers at isolation sites to ensure The variant strain does not cause further transmission in our province.
Publisher: Zhenglong
