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Original title: 2020 Future Science Award Announced: Zhang Tingdong, the founder of arsenic treatment of leukemia, and four others won the award with a prize of up to one million US dollars
September 6 was named “China’s Nobel Prize”,cousinUp to a millionAmerican dollarThe winners of the Future Science Awards 2020 were announced in Beijing.
Among them, Zhang Tingdong and Wang ZhenyiborrowHe discovered the therapeutic effects of arsenic trioxide (arsenic) and trans-retinoic acid in acute promyelocytic leukemia and won the “Life Sciences Award”; Lu Ke achieved this by his pioneering discovery and use of twin nanostructures and gradient nanostructures. The high strength, high toughness and high electrical conductivity of copper metal won the “Materials Science Award”; Peng Shige was awarded for his pioneering contributions in the theory of backward stochastic differential equations, the nonlinear Feynman-Kac formula and the theory of nonlinear mathematical expectation. “Mathematics andcomputerScience Award “.
It is worth noting that Zhang Tingdong, the winner of the Life Sciences Award, is the founder of the use of arsenic (arsenic trioxide) in the treatment of leukemia, and is considered one of the expected mainland Chinese scholars win the Nobel Prize in Physiology or Medicine. Telephone of the Organizing Committee of the Future Science AwardsnoticeWhen Wang Zhenyi, the other party expressed a mixture of happiness and sadness.jobsBe recognized andexcitementHis concern is that he is 96 years old and the award should go to young people who are working.
Based on the winning results revealed that day,The winners of the “Life Science Award” are Zhang Tingdong and Wang Zhenyi. Award Winner’s Comment: Reward them for discovering the therapeutic effects of arsenic trioxide and trans-retinoic acid on acute promyelocytic leukemia.
Cancer continues to be a great threat to human health. In the process of human exploration of cancer treatment, Zhang Tingdong and Wang Zhenyi have made decisive contributions to curing acute promyelocytic leukemia (APL). APL used to be one of the most dangerous and deadly leukemias. The work of Zhang Tingdong and Wang Zhenyi made the APL cure rate reach 90%. For thousands of years, arsenic trioxide (ATO, commonly known as arsenic) has been tested in many different diseases, but its curative effect has not been reliable, repeatable, or recognized. In the 1970s, research by Zhang Tingdong and his colleagues made it clear that ATO can treat APL for the first time. In the 1980s, Wang Zhenyi and his colleagues demonstrated for the first time that all-trans retinoic acid (ATRA) has a significant therapeutic effect on APL in patients. The work of Zhang Tingdong and Wang Zhenyi has been verified and promoted internationally, making ATO and ATRA the standard drugs for the treatment of APL leukemia in the world today, saving the lives of many patients.
Zhang Tingdong, born in Hebei in 1932, the first affiliated hospital of Harbin Medical Universityprofessor. Wang Zhenyi, born in Shanghai in 1924, ShanghaitrafficCollege professor.
The winner of the “Materials Science Award” is Lu Ke. Awardee’s Comment: He was rewarded for his pioneering discovery and use of twin nanostructure and gradient nanostructure to achieve high strength, high toughness and high conductivity of metallic copper.
Improving the strength of metallic materials has always been one of the fundamental scientific issues in the field of materials physics. Generally, the reinforcement of the materials is achieved by introducing various defects that hinder the movement of the dislocations. However, when the resistance of the material is increased, plasticity and conductivity will be lost. This has given rise to the famous material of resistance and plasticity (or Electrical conductivity). How to overcome this contradiction has become a major scientific problem in the field of international materials for decades.
Lu Ke and his researchequipmentIt was found that two new nanostructures can increase the strength of copper metallic materials without losing their good plasticity and conductivity, and a breakthrough has been achieved in the principle of strengthening metallic materials.
Lu Ke’s team found that introducing high-density nano-twin interfaces in metallic copper can increase the strength of pure copper by an order of magnitude, while maintaining good tensile ductility and high electrical conductivity (equal to high purity oxygen free copper). Nano-twinned copper obtained with ultra high resistance and high conductivity. This discovery breaks the force-conductivity inversion relationship and opens a new direction of research in nanometal materials. The principle of nano twins reinforcement has been verified and applied in a variety of metals, alloys, composites, semiconductors, ceramics and diamonds, and has become a universal principle of material reinforcement.
Lu Ke’s team also discovered the gradient nanostructure of metals and their unique reinforcement.mechanism. The gradient nanostructure can effectively suppress the concentration of deformation and realize non-localization of deformation, and its tensile plasticity is better than that of ordinary coarse-grained structure. Pure copper with gradient nanostructureshowsIts strength is twice that of ordinary coarse-grained copper, while its tensile plasticity remains unchanged. It also breaks the resistance-plasticity inversion relationship of the traditional reinforcement mechanism. It’s used inindustryAnd achieved significantEconomic benefit。
Lu Ke, born in 1965, is an academic at the Chinese Academy of Sciences, a researcher at the Metal Research Institute of the Chinese Academy of Sciences, and director of the Shenyang National Research Center for Materials Science. Public information shows that Lu Ke was born in 1965. In addition, Lu Ke is also vice president of the Central Committee of the Jiu San Society. He was elected deputy governor of Liaoning Province in October 2018.
The winner of the “Mathematics and Computer Science Award” is Peng Shige Recipient’s Comment: Rewarded for pioneering contributions in the theory of backward stochastic differential equations, the Feynman-Kac nonlinear formula, and the expectation theory nonlinear mathematics.
Professor Peng Shige has made innovative and pioneering contributions in the fields of backward stochastic differential equations, nonlinear Feynman-Kac formulas, and nonlinear mathematical expectations.
The article published by Peng Shige and Pardoux in 1990 is considered the foundational work of the Theory of Stochastic Backward Differential Equations (BSDE). This work has created an important field of research, including both deep mathematical theories and important applications in mathematical finance. Peng has been continuously working in this field and has made a number of important contributions.
Peng Shige created the Feynman-Kac nonlinear formula in 1992, thus giving a BSDE representation for a large class of second order nonlinear differential equations.
Peng Shige developed the theory of nonlinear mathematical expectation, which is essentially different from traditional linear mathematical expectation, but similar mathematical theories can still be established. This has important applications for the definition and quantification of risks.
Professor Peng Shige was born in Shandong in 1947. He received his doctorate from the Université Paris Dauphine in 1985 and from the University of Provence in 1986. He is currently a professor at the University of Shandong.
As China’s first privately sponsored science award, the Future Science Award emphasizes awards for scientific research that has been completed in Greater China, has great international impact, is original, has long-term significance, or has passed. the test of time. The Future Science Awards evaluation system mainly refers to the Nobel Prize, the Turing Prize and other internationally renowned prizes, and adopts the system of invitation for nominations and the international peer review system. Since 2016, 20 Future Science Award winners have been selected and wonsocietyWide recognition in the field. All of them are highly successful scientists in the fields of basic and applied research such as life sciences, physics, chemistry, mathematics, and computers.
The one-time Future Science Award is one million US dollars (RMBApproximately 7 million yuan), each voucher is donated by four donors: Ding Jian, the donor of the “Life Sciences Award”Li Yanhong、Shen nanpeng、Zhang Lei; The donors of the “materials science award” are Deng Feng, Wu Yajun, Wu Ying,Xu Xiaoping; The donors of the “Mathematics and Informatics Award” are Ding Lei,Gangnam Spring, Ma Huateng, Wang Qiang.
(Source: 21st Century Business Herald)
(Responsible editor: DF075)
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