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Original Title: Is It Effective Against Mutant Strains? AstraZeneca Vaccine Staggered Research Results Released
AstraZeneca Pharmaceuticalsthe companyOn day 6 it was confirmed that preliminary research data showed that the new corona vaccine developed by AstraZeneca had “limited” protection against people slightly infected with the new mutant corona virus originally discovered in South Africa. However, according to researchers at the University of Oxford in the UK, this vaccine appears to be effective against the new mutant coronavirus that was originally discovered in the UK.
Variants found in South Africa: limited effectiveness
UK”Financial timesHe reported on day 6 that a joint study by South Africa’s Golden Mountain University and Oxford University showed that the new mutant coronavirus originally discovered in South Africa “severely weakened” the efficacy of the AstraZeneca vaccine.
It reported that 2,026 people participated in this study, half of whom participated in the control group. The mean age of the subjects was 31 years and no subject was admitted to the hospital or died.
In response to the previous report, an AstraZeneca spokesperson said: “In this small phase I and II trial, preliminary data shows that the vaccine has limited protection for patients with new mild coronary disease. The main reason is the B mutation. .1.351 (first discovered) in South Africa. Virus strain “.
The spokesperson said that since the majority of study subjects are healthy young adults, the effectiveness of the AstraZeneca vaccine for critically ill patients cannot be determined at this stage, but AstraZeneca is confident that the vaccine can protect critically ill patients. .
This vaccine developed jointly by AstraZeneca and the University of Oxford has been approved for commercialization in many countries. The spokesperson said: “The University of Oxford and AstraZeneca have started to improve the vaccine so that it can deal with this mutant virus. Clinical trials will be accelerated, with a view to its availability in the fall.
Variant found in the UK: appears to be effective
Oxford University confirmed on day 5 that ongoing evaluations show that the current AstraZeneca vaccine is as effective against the mutant strain originally found in the UK as against other strains.
Andrew Pollard, a researcher at the New Coronary Vaccine Project at the University of Oxford, said that data from research conducted in the UK showed that “this vaccine is not only effective against the original novel coronavirus, but also against the new variant of the virus. (found in the UK) B.1.1.7. “.
Samples from the previous study were collected from October last year to mid-January this year.
Sara Gilbert, another senior researcher at the University of Oxford, said: “We have always predicted that as the epidemic continues, mutant strains will become ‘mainstream’ and eventually a new version of it may be needed. vaccine”.
An article in the British Medical Journal stated that the new coronavirus has thousands of variant strains, and only a small part has changed significantly. According to Reuters, what worries scientists and public health experts most at this stage is that the three mutant strains originally discovered in the UK, South Africa and Brazil are spreading faster.
The results of the two previous studies on the efficacy of AstraZeneca vaccine against variant strains have not been published in any peer-reviewed medical journal.
(Source: Xinhua News Agency)
(Responsible editor: DF513)
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