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It seems that the battle against the new corona virus has vastly increased humanity’s chances of victory. A more optimistic view is that victory is in sight.
In the last 10 days, there have been several good news related to vaccines.November 9，Pfizer and BioNTechIt announced that their joint research and development of the new corona vaccine has an effective rate of 90%; two days later, a Russian pharmaceutical company announced that its new previously registered crown vaccine Spoutnik V has an effective rate of 90%; This Monday, the American biotechnology company Moderna announced that they had developed The effective rate of the new corona vaccine is 94.5%.
Moderna announced more details, such as its vaccine products andPfizer and BioNTechIn comparison, the advantage is that it does not require harsh storage and transport conditions. It can be stored for 30 days in 2-8 degree Celsius environment. In an environment of minus 20 degrees Celsius, this time limit can be extended to 6 months.
And Spoutnik V is the world’s first registered new corona vaccine. A Russian deputy prime minister endorsed its safety and efficacy through personal vaccination, but the vaccine initially encountered widespread suspicion in the international scientific community, because Russia did not publish any clinical trial data at the time, “The Lancet.” Subsequently, the journal published articles related to this vaccine and, according to the articles, the protective effect of this vaccine is real and effective.
this Wednesday,Pfizer and BioNTechDrop againThe results of the phase III clinical trial of its new corona vaccine: Among the 43,000 subjects, 170 were infected, of which 8 were in the vaccination group and 162 in the placebo group; Of the 170 infected, there were 10 serious infections, of which 9 were from the placebo group and the vaccination group. There is only 1 person. End-point analysis showed that the protection of this vaccine reached 95% in the population vaccinated for the first time and 94% in the 65-year-old group.To the United States Food and Drug Administration (FDA)Apply for USA, the standard for emergency use authorization.
This good news is enough to make people forget as soon as possible the embarrassment that Pfizer’s CEO took advantage of the spike in the company’s stock price caused by the good news about the vaccine and charged $ 5. millions.
The best news is that this vaccine has not found any serious safety risks in clinical trials, and the main adverse reactions are fatigue and headache.Pfizer andBioNTechHe said he will submit an application to the FDA in a few days and plans to launch 50 million vaccines in 2020; in 2021, 1.3 billion vaccines will be launched.
Since the new coronavirus began to spread globally in early 2020, how to effectively fight this enemy of all humanity, from international organizations to the governments of all countries have considered vaccine research and development as the ultimate weapon, and the vaccine research and development competition has also started for the first time.
According to data published by the World Health Organization on November 12, 11 of the 48 new coronavirus vaccines currently in clinical trials around the world have entered phase III clinical trials and have begun to be vaccinated in tens of thousands of volunteers to test its effectiveness. With adverse reactions. The other 37 species are still in phase I or II clinical trials, which means they are still testing their basic safety and efficacy. In addition to these 48, there are 164 vaccine programs that have not yet entered clinical trials.
The world’s leading pharmaceutical companies are actively joining the ranks of research and development for new corona vaccines. But the process has not been easy.
AstraZeneca had previously stopped the test due to an unexplained adverse reaction in a subject, but it quickly returned to normal. China Kexing Company’s new crown vaccine was also temporarily discontinued due to its involvement in an “Oolong Incident” in which a Brazilian subject died. When police confirmed that the subject died by suicide and had nothing to do with the vaccination, the trial was resumed.
At Pfizer andBioNTechAfter the good news of the two vaccines with Moderna, Zhong Nanshan is highly respected by the Chinese government and the private sector.A medical expert said:“Pfizer’s vaccine () can prevent 90% of infections. In fact, Guangdong and China’s vaccine research and development are at the same level, but the results of the first phase can only be announced,” Gao Fu said. , director of the National Center for Disease Control and Prevention of China, at a meeting. China asks people to believe that “China’s vaccine is also very effective.”
Vaccines that have been highlighted by the media and their astonishingly sounding efficacy have increased people’s confidence to return to normal life. But even if scientists in general are satisfied with the speed and results of the current development of the new corona vaccine, it should be clear that even the most recognized vaccines in clinical trials still have a limited number of subjects, which obviously it will affect them. Effect judgment, and if 90%, 92% or 94% of the effectiveness is currently known, it is published by pharmaceutical companies through the media, not through scientific journals, that is, it has not been effective. Peer Review.
Although scientists have repeatedly emphasized that, according to normal scientific laws, it takes several years for a vaccine to go from research and development to market launch, and the new corona epidemic clearly does it as quickly as possible. , adhere to scientific principles and guarantee safety. Hand and Foot Attempts: In human history, there has been no vaccine that can give humans possible protection at this rate.
But even if the vaccine is on the market, it really shows the effect, that is, it helps people to resist and defeat the new corona virus, it is not something immediate. This effect can only manifest itself when a high proportion of people are vaccinated, however, it is not easy to inject the “high proportion of people”.
The unscientific “harmful vaccine theory” has long existed as a conspiracy theory. After the outbreak of the new crown epidemic, this argument became rampant again, and an improved version was even derived. For example, the new corona epidemic was artificially created to induce large numbers of people to get vaccinated. Royal Society Scientific Publications《Royal Society Open Science》According to a study carried out by, 22% of people in Mexico believe this statement. Earlier this year, Bill Gates came under fire because of the importance of vaccines.
Regardless of the reason for the rejection of the vaccine, the prevention and control of the new corona epidemic will not change immediately due to the appearance of the vaccine. In addition to ensuring the effectiveness of the vaccine, scientists, pharmaceutical companies and government departments must persuade people to inject the new corona vaccine to achieve the immune effect.
This is likely to be a more difficult task than vaccine research and development. According to a survey of 15 countries conducted by the World Economic Forum, only 73% of people expressed their willingness to receive the vaccine. This ratio has decreased compared to August.
While the good news about vaccine development continued to spread, the number of infected people in the United States increased from 10 million to 11 million in just 11 days. At the same time, many states began to adopt new epidemic prevention measures. However, these external measures cannot compel people to get vaccinated.
To end the new crown with a vaccine, successful research and development is only the first step in the long march to convince people that science is the last mile to victory. (Chinese network of fortune)
