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Scientists warn that even if a new effective corona vaccine is successfully developed, it will not be able to return to normal life in the spring of 2020.
Vaccines are often seen as the antidote to ending the new corona pandemic. But a research report led by the Royal Society stated that we must be realistic about the purpose and timing of vaccine prevention. Scientists involved in the study said that social restrictions may need to be gradually relaxed and that the vaccine may take a year to get vaccinated on a large scale.
Scientists around the world are developing more than 200 new coronavirus vaccines at an unprecedented rate.
Dr Fiona Culley of Imperial College London’s National Heart and Lung Institute said: “Vaccines offer great hope to end the new corona pandemic, but the history of vaccine development is full of many Failure situation “.
Optimists, including British government scientific advisers, believe that some people may be vaccinated this year, and mass vaccination may begin early next year.
But the Royal Society report warns that it will be a long process.
Professor Nilay Shah, head of chemical engineering at Imperial College London, said: “Even if there is a vaccine, it does not mean that all employees can get vaccinated in one month. We mean six months, nine months or even a month.” Years.”
According to the report, there are huge challenges ahead. For example, RNA vaccines have never been mass produced before. RNA refers to the genetic code of the new coronavirus. Currently, RNA vaccines use RNA to produce viral proteins to trigger an immune response.
Outsiders have questions about the freezer capacity of some vaccines and glass vaccine vials, and some vaccines need to be stored at -80 ° C.
Professor Sha estimated that the vaccination rate should be 10 times faster than the annual influenza vaccination rate, and will be carried out by up to 30,000 full-time trained people. He said, “I’m very worried, does the whole system have enough thinking?”
Early test data indicates that the vaccine is triggering an immune response, but research has not yet shown whether the vaccine is sufficient to provide comprehensive protection or reduce symptoms of the new coronavirus.
Leung Zhuowei, dean of the University of Hong Kong School of Medicine, said in an interview with Hong Kong media that most vaccines in development cannot 100% prevent vaccinators from contracting a new coronary pneumonia. Its main effect is to reduce mortality or serious complications. The elderly group or the group with chronic diseases.
Unanswered question
Professor Charles Bangham, Head of the Department of Immunology at Imperial College London, said: “We do not know when an effective vaccine will be successfully developed, how effective it will be, and of course when it will be distributed. Even if the vaccine is effective, It is unlikely that we will fully return to normal life … In addition, we will have to gradually relax some (social restrictive) interventions. “
Many questions that determine vaccination strategies remain unanswered, such as:
- And we still don’t know if one shot of the vaccine is effective or if more are needed?
- Is the vaccine effective enough for older people with aging immune systems?
The researchers caution that it will take time to answer the question of long-term immunity, and we don’t yet know whether the public needs a vaccine every two years or a single injection.
Leung Zhuowei, dean of the University of Hong Kong School of Medicine, said vaccines in the third phase of clinical trials should cover dozens of new coronavirus strains. It is expected that after vaccination, the public will have to repeat it in 9, 12 or 18 months. Vaccination requires a longer observation at this stage.
Earlier, the head of the China National Pharmaceutical Group said that once the vaccine developed by the company hits the market, citizens must receive two injections to produce enough antibodies.
Commenting on the Royal Society research, Dr Andrew Preston of the University of Bath said: “Obviously the vaccine is presented as a savior, but this may not be immediate.”
He said that in the future, it is necessary to discuss whether a “vaccine passport” is required to enter a country to demonstrate immunity to the new coronavirus.
Dr. Preston cautioned that the wavering attitude toward vaccination appears to be a growing problem, which has become an anti-mask and anti-block idea. “If a group of people refuses to get vaccinated, do we take the approach of letting them fend for themselves or forcing school students and nursing home staff to get vaccinated?