Two coronavirus drugs used in cats can help humans infected with the novel coronavirus, according to a preliminary study recently published in the journal Nature.
Drugs known as GC376 and GC373, diptide-based protein inhibitors, are designed to treat cats with infectious peritonitis of the cat, a potentially fatal disease caused by another type of coronavirus, cat anti-coronavirus (FCOV). The publication explained that FCOV is a coronavirus that has similar characteristics to SARS-CoV-2, causing the virus COVD-19.
Joan Lamiax, a professor in the Department of Biochemistry at the University of Alberta, said, Stated in the publication. Success in treating cats with the help of drugs could help humans infected with COVID-19, the researchers said.
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“In cats, GC6 converts the (proprug) to GC7373 to and was able to successfully treat cats without any toxins. Of the 20 cats tested, 19 recovered, ”Lamiax said in a statement.
According to a preliminary study recently published in the journal Nature, two coronavirus drugs used in cats can help humans infected with the novel coronavirus.
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Researchers at the University of Alberta in Canada believe that the drug inhibits the enzyme produced by cats’ anti-coronavirus, preventing them from reproducing, thus stopping infectious peritonitis in cats. This could work in a similar way to fight novel coronavirus in humans, they said.
“Studies have shown that GC The376 and GC737373 were effective in targeting proteases for both SARS-Cavi and SARS-Cavi-2.”
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“GC7373. and GC6376 are potent inhibitors of SARS-COVI-2 replication in cell culture. They are strong candidates of the drug for the treatment of human coronavirus infections as they have already been successful in animals, ”the authors said.
“Not surprisingly, cats can be treated with COVID-19, especially since the drug targets the main proteases of the virus, which is very safe,” Lamix said.
Lemieux said the findings lay the groundwork for human trials, adding that the researchers had received a grant to start trials in Canada. Researchers are also conducting clinical trials in the United States, in a recent publication.
