Biontech / Pfizer: This graph shows the effect of corona vaccination



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Panorama Biontech and Pfizer

This graph shows the effect of corona vaccination.

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A shovel the world watches: British start corona vaccines

Margaret Keenan, 90, will surely go down in history. She is the first woman outside the study to be vaccinated with the Biontech-Pfizer corona vaccine. This marked the start of what is probably the country’s largest vaccination campaign in Great Britain.

The Biontech vaccine could provide 95 percent protection against corona virus infection. What this could mean for the infection curve is shown in a graph from a US FDA report.

rehe first patients in Britain have already been vaccinated: the crown vaccine from Pfizer and Biontech is the first vaccine against Sars-CoV-2 approved in a Western country. On Twitter, a graphic is now circulating with data that the drug company uses to seek approval from the US FDA.

Shows the number of new infections from 38,000 test subjects who were recorded in two test groups in the clinical study of the vaccine: first, infections in the group injected with a placebo, and new infections in those who received the vaccine. vaccine. The curves are similar in the first days after the injection. That changes after 10 to 14 days, when the curve in the placebo group continues to rise steadily, while hardly any new infections are recorded in the other test group.

“Based on the cumulative incidence curve of all test subjects after the first dose of vaccination, both groups, BNT162b2 and placebo, experienced a similar frequency of Covid 19 symptoms in the first 14 days after the dose. The curves diverge after about 14 days. More cases accumulate in the placebo group than in the BNT162b2 group, and there is also no evidence that protection decreases in the next two months after the second dose … “, says the report. .

BNT162b2 is the official name for the vaccine, which, based on initial clinical testing, is said to be around 95 percent effective. Manufacturers recommend two vaccines with an interval of 21 days, the maximum vaccination protection should be given approximately four weeks after the first vaccination. According to the graph, some vaccine protection could exist earlier.

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On Tuesday night, many findings from the FDA report circulated on Twitter. A post by immunologist Florian Krammer, who is researching antibodies to influenza viruses in the US, received a lot of attention. “That doesn’t need words. This is how vaccines work, ”he wrote in a screenshot of the graphic above.

The American pharmaceutical company Pfizer and the Mainz-based company Biontech are currently applying in several countries and in the EU for express approval of their vaccine. In the United States, the FDA is responsible for this.

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A virologist poses with a syringe for vaccination against the corona virus.  (Symbol photo with model) Nuremberg, April 23, 2020 |  Use all over the world

Last week, Britain became the first country in the world to grant emergency approval of the corona vaccine. First, nursing home residents, medical staff, the elderly and the endangered have been vaccinated since Tuesday. Four million doses of vaccines are expected to arrive in the country this year; In all, London has ordered 40 million doses of vaccines from Pfizer. Hundreds of millions more doses are expected from other vaccine manufacturers whose preparations have not yet been approved. Products from domestic manufacturers are already used in China and Russia.



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