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Race for a vaccine: Berlin Charite sees the basis for so-called passive vaccination.
10:22 pm, September 24, 2020
According to their own statements, the Berlin researchers have discovered “highly effective” antibodies against the coronavirus. Scientists from Charite and the German Center for Neurodegenerative Diseases are now following the development of so-called passive vaccination, Charite announced Thursday. Then i could Antibodies administered will be, to provide instant protection – preventively or even for those who are already sick.
The researchers isolated nearly 600 different antibodies from the blood of people who survived corona disease. Then, particularly efficient specimens could be artificially propagated. According to the information, they bind to the virus, preventing it from entering cells and multiplying.
Treatment and prevention
Therefore, studies on hamsters proved its efficacy. “If the antibodies were administered after an infection, the hamsters developed at best mild symptoms of the disease,” reported the coordinator of the research project. Jacob creates. With preventive administration of the antibodies, animals do not get sick in the first place.
Three of the antibodies identified so far for clinical development are particularly promising, according to Charite. In addition to the treatment of sick people, the preventive protection of healthy people who have had contact with infected people is a possible application. The researchers work with the Miltenyi Biotec company.
The difference with an active vaccination is that with passive vaccination finished antibodies administered will be the degraded after a certain time will be. Generally is Protection against passive vaccination is less permanent than through an asset. “For this, the effect of a passive vaccine is available almost immediately, with an active vaccine it has to accumulate first,” he said.
