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Mr. Ho Nhan and the preparation of the Nanocovax nasal spray vaccine – Photo: L.ANH
This morning, December 10, the inauguration ceremony of the clinical research of the COVID-19 vaccine developed by Nanogen Company, Vietnam took place at the Hanoi Military Medical Academy.
30 people signed up for the test injection in the first hour. The research team is still recruiting volunteers to participate in the test injections.
Mr. Ho Nhan, President and CEO of Nanogen Company, said that the Nanocovax vaccine is a recombinant protein S vaccine, which is a peak of the SARS-CoV-2 virus, with 4 doses of 25 mcg, 50 mcg. , 75 mcg, 100 mcg.
Nanocovax nasal spray for children under 12 years old, people with underlying diseases, the elderly – Photo: QUANG HUNG
Through tests in white mice, hamsters, monkeys and rabbits, the results showed that the vaccine guarantees safety.
In terms of immunogenicity, Nhan said he tried it at the National Institute of Hygiene and Epidemiology, created a human-like ACE2 receptor in hamsters, injected 2 doses of vaccine, and injected the virus into control mice, and the mice were vaccinated. .
The results of mice vaccinated with normal weight gain, normal feeding and drinking and mice without vaccines were clearly diseased. When sampling, vaccinated mice were negative, non-injected mice positive for COVID-19.
A large number of participants signed up to voluntarily test the COVID-19 vaccine this morning – Photo: L.ANH
Mr. Nhan also shared that the COVID-19 vaccine is similar to the seasonal flu vaccine, it has a protective effect for 6 months and needs to be vaccinated again every year.
Because the virus strain has changed, the strain in Wuhan, China at the beginning of the epidemic was different from Europe in April-May, later in July, when the epidemic appeared in Da Nang, the team had a new strain. creating a common strain, and the modified vaccine strain can still adapt.
In addition to the injectable vaccine, Nanocovax also produces a nasal spray vaccine that can be used for children under 12 years of age, people with background diseases, over 70 years …
The strong point of Vietnamese vaccines is that they can be stored at a normal refrigerator temperature (2-8 degrees), while vaccines from some manufacturers must be stored at minus 75 degrees, which makes it difficult to preserve. transport.
“Because this vaccine is ordered and subsidized by the state, the price of a vaccine is only 120,000,” Nhan said.
According to Mr. Do Quyet, Director of the Military Medical Academy, the unit conducting this clinical trial, at the beginning of the clinical trial, Vietnam was one of 40 countries that tested the COVID-19 vaccine. in body.
“We have produced very early and quality test COVID-19, now we have the COVID-19 vaccine. We have been sitting equally, sitting at a round table with international standards in various fields of biomedical research. “- Mr. Quyet shared happily.
The Nanocovax vaccine contains 100% protein S in pure form and aluminum excipients. Each batch can produce 600,000 doses, the current capacity is 10-12 million doses / year, but the Nanogen company has a project to increase the capacity to 50-70 million doses / year.
