Oncologists talk about the ‘downside’ of early cancer detection



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Thursday, November 19, 2020, 7:00 pm (GMT + 7)

Tumor markers (tumor markers) are mass produced by tumors that can distinguish benign tumors from cancer or detect tumors using blood tests.

Oncologists talk about the 'flip side' of early cancer detection - 1

Tumor markers (tumor markers) are mass produced by tumors that can distinguish benign tumors from cancer or detect tumors using blood tests. Some tumor markers are specific to one type of cancer, others are found in many types of cancer. Most tumor markers increase in non-cancerous diseases. Therefore, the use of tumor markers alone is not a cancer diagnostic tool.

Ideal characteristics of tumor markers should include:

1. Specificity and specificity (specificity).

2. Corresponding to the size and activity of the tumor.

3. Only positive when it is cancer.

4. Positive early in the development of malignancy.

5. Easily measurable.

Currently, there are no TUMOR MARKERS that satisfy all of the above criteria. Most tumor markers are found in normal tissues, benign and malignant tumors and are not specific enough to be used for cancer detection.

For example, CEA is a cell surface protein that is a marker for colorectal, gastrointestinal, lung, and breast cancer. CEA also increased in smokers, cirrhosis, rectal polyps, rectal ulcer disease, benign breast disease. Do not use CEA for cancer detection. In contrast, a person with stomach cancer does not necessarily have an elevated CEA.

CA 19.9 is a marker for colorectal and pancreatic carcinoma. However, it can also be increased in patients with hepatobiliary, gastric, hepatocellular cancer and many benign diseases such as pancreatitis, gastrointestinal disease.

Tumor markers are only involved in the approach to diagnosis, but they are not used alone to diagnose cancer, much less to evaluate early detection of cancer. Tumor markers in cancer patients correspond to the size and / or activity of the tumor. But not all cancers increase tumor markers. Tumor markers are mainly used to classify risks, prognosis, monitor response to treatment, suspected recurrence of cancer patients.

Overuse of tumor marker tests does more harm than good. There was a patient with cancer, and if he didn’t see an increase in the cancer mark, he said “I must have a benign tumor.” Some healthy people find their test results higher than the benchmark, panic, lose their appetite, lose sleep, and even drink sweet marijuana leaves immediately.

Therefore, the cancer diagnosis includes asking about medical history, age or cancer, risk factors, exposure history, physical examination to detect symptoms and injuries, ultrasound, imaging, biopsies make anatomical diseases, use tumor markers that think about certain organs / tumors …

Source: https: //www.tienphong.vn/suc-khoe/bac-sy-ung-thu-noi-ve-mat-trai-cua-xet-nghiem-sang-loc-ung-thu …

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