Clostridium botulinum Poisoning From Eating Pate Minh Chay: Enter an antidote of $ 8,000 / bottle | News



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On August 31, Dr. Le Quoc Hung, Head of Cho Ray Hospital for Tropical Diseases (BV) (Ho Chi Minh City), said that the hospital had received and treated patient (patient) NND (54 years old, who lives in Ms. Ria-Vung Tau) in critical condition from eating Minh Chay pate.

More than 30 years in the profession just completed

According to Dr. Hung, on the night of August 25, Minh Chay ate a lot of pate. At 11:00 p.m. on August 26, the patient presented abdominal pain, vomiting, difficulty swallowing, difficulty speaking and drooping eyelids, he was transferred to Ba Ria-Vung Tau Hospital in a state of limb weakness, total collapse, difficulty to breathe, later. He was then transferred to the Cho Ray hospital on August 27 with a diagnosis of myasthenia gravis and sent to the neurology department.

Clostridium botulinum poisoning from eating Pate Minh Chay: Enter an antidote of $ 8,000 / bottle - Photo 1

Pate Minh Chay has toxic bacteria Clostridium botulinum

However, since the patient’s condition was not the same as the myopathy, the physician (BS) who had diagnosed and suspected a Clostridium botulinum poisoning should be transferred to the department of tropical diseases. The patient is awake, has no fever and paralysis has not improved, is on mechanical ventilation. BV also filters the patient’s blood and prevents complications caused by the toxin Clostridium botulinum. Because Vietnam currently has no antidote, patients receive supportive treatment with mechanical ventilation, dialysis … “For more than 30 years in the profession I have not encountered this type of poisoning. Doctors of the older generation said they met sporadically in the 1980s and took them to Cho Ray Hospital, ”said Dr. Le Quoc Hung.

Thus, this is the sixth case of hospital admission to Cho Ray hospital after eating Minh Chay’s pate (5 previous patients were discharged from the hospital to continue treatment in the localities). Also at the Ho Chi Minh City Hospital for Tropical Diseases, there are also 2 cases in treatment with 1 case still ventilated.

Meanwhile, on the night of August 31, Dr. Tran Van Song, deputy director of People’s Hospital 115 (Ho Chi Minh City), said that the hospital had also accepted patients with high school health (41 years old, living in Thu Dau Mot City, Binh Duong) in Severe Condition after eating Minh Chay pate. BV has changed plasma 5 times, with mechanical ventilation, used infusion, antibiotics, supportive treatment. Currently, the patient is awake, able to contact. The strength of the muscles in my limb improved by 4/5 but the respiratory muscles were still weak, so the ventilator could not be stopped.

You must enter the medication urgently

At the Bach Mai Hospital Poison Center (Hanoi), 2 married patients (Mr. Đ.GT, 70 years old, and Mrs. TBL, 68 years old), were poisoned with Clostridium botulinum after eating together. Minh Chay pate. Two hospitalized patients with diffuse paralysis, paralysis of the head, face and neck extending to the arms, legs and dilated pupils.

Two sisters poisoned with pate Minh Chay in Ho Chi Minh City are still on mechanical ventilation

The patient said that last July he bought Minh Chay pate online and used it gradually. The last meal was at the end of July, the symptoms appeared shortly after, the two grandparents were admitted to the geriatric hospital and then transferred to the Bach Mai hospital for treatment on August 18. .

Dr. Nguyen Trung Nguyen, director of the Bach Mai Hospital Poison and Control Center, said that two patients still completely paralyzed their muscles from head to toe, could not breathe, had to rely on ventilators, and had a fairly severe prognosis. . These are the first cases of Clostridium botulinum poisoning at Bach Mai Hospital in many years. Because there is no antidote for Clostridium botulinum in Vietnam, the Bach Mai Hospital immediately sent a report to the Ministry of Health for the report. Soon after, the Bach Mai Hospital, Ministry of Health, World Health Organization (WHO) had to work very urgently to bring 2 vials of antidote from a poison control center in Thailand to Vietnam. In 10 days.

” On August 29, 2 vials of antidote were transported to Vietnam and used immediately for 2 patients. The price of each bottle of this medicine in Thailand is up to 8,000 USD and currently the WHO covers the full cost, ”said Dr. Nguyen, adding that in cases with milder signs, patients only treat symptoms, or treatment ambulatory. “If you continue to have more serious cases, the supply of drugs will be very difficult,” said Dr. Nguyen.

1,290 people at HCMC bought Pate Minh Chay

Regarding the hospital case after using Minh Chay pate products, on August 31, Assistant Professor Dr. Luong Ngoc Khue, Director of the Department of Medical Services Administration (Ministry of Health), sent a document expressing promptness to Bach Mai Hospital (Ha Noi), Cho Ray Hospital and Ho Chi Minh City Hospital for Tropical Diseases, suggest a list of cases with signs of Clostridium botulinum toxin infection with a history of using Minh Chay pate; provide expertise in diagnosis, detection and treatment; Brief report on the evolution of the case and the current status of the patient. The Ministry of Health will issue general guidelines for hospitals on case detection and diagnosis for early detection and timely management when new cases are detected.

In another development, on the morning of August 31, Associate Professor Dr. Pham Khanh Phong Lan, head of the Food Safety Management Board (Food Safety) in Ho Chi Minh City, sent an official dispatch to 24 districts in the area on emergency product management. Unsafe products related to hospitalized patients after eating Minh Chay pate. The Food Safety Management Board requests the People’s Committee of 24 districts to inspect and control the market, proactively recall the products of New Lifestyle Two-Member Limited Company (group 2, Dong Anh TT, Dong Anh District, Hanoi) and specific announcements About Ban including 13 products: Minh Chay Pate, Lion’s Mane Mushroom Pate, Heri Premium Mushroom Soup, Special Sesame Salt, Heri Heri Mushrooms, Rice Silk Rolls Blind Peanut Salt, Traditional, Cinnamon Rolls and wheat, sesame salt, wheat mushroom rolls, traditional mushroom rolls, lemongrass and chili mushrooms, garlic flames.

PGS-Dr. Lan also said that the Food Safety Management Board has verified 1,290 customers in Ho Chi Minh City who purchased 1,559 boxes of Minh Chay pate in July and August 2020 online. Buyer has been contacted for discontinuation and withdrawal. The Board is currently conducting a review of the stores.

The virulence of the bacterium Clostridium botulinum is very strong

Previously, the Department of Food Safety (Ministry of Health) announced urgently from July 13 to August 18 that 9 cases of disease from various provinces of the country should be treated at the Bach Mai Hospital (2 cases), Cho Ray Hospital (5 cases, excluding new cases) and HCMC Tropical Disease Hospital (2 cases).

Hospitalized patients with symptoms of fatigue, drooping eyelids, weak limbs, difficulty swallowing, muscle paralysis, shortness of breath … Through the investigation it was shown that all the patients were using Minh Chay pate products from two joint stock companies. New members of Lifestyle.

Initial test results of some Minh Chay pâté products from different batches showed that Clostridium botulinum B bacteria have very strong virulence, severe health effects, prolonged and easily fatal.



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