Could the SARS-CoV-2 variant inactivate a Covid-19 vaccine made in Vietnam?



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According to a report by the World Health Organization, a new variant of the Covid-19 SARS-CoV-2 virus first discovered in the UK has spread to 50 countries and territories. Variants have also appeared in South Africa in 23 countries and regions. In Southeast Asia, the development of the disease is complicated and there is a potential risk of new outbreaks.

Concerned that the new SARS-CoV-2 strains could cause the vaccines being studied to be unprotective, Prof. Dr. Dang Duc Anh, Director of the National Institute of Hygiene and Epidemiology, indicates that the SARS-CoV-2 variant is mutated only in some points, so it does not affect the Covid-19 vaccine.

Could the SARS-CoV-2 variant inactivate a Vietnamese-made Covid-19 vaccine?  Photo 1.

The Covivac vaccine began to be tested in volunteers

“The Covivac vaccine is a Newcastle vector (NDV) vaccine that has been officially tested in volunteers with the SARS-CoV-2 protein S expression gene. Scientists use the S protein from the virus. Today, the world has registered mutations in some virus strains in England and South Africa, in which, some points are registered in the gene encoding S .. However, the protein S segment is quite long while the mutation is only At some points , not in all, in general, the SARS-CoV-2 strain will not affect the research and production of the Covid-19 vaccine ”, analyzed Professor Duc Anh.

Could the SARS-CoV-2 variant inactivate a Covid-19 vaccine made in Vietnam?  - Photo 2.

Prof. Dr. Dang Duc Anh, Director of the National Institute of Hygiene and Epidemiology

Also according to Professor Duc Anh, in the world, the Covid-19 vaccines that are being studied also do not affect the antigen and immunogenicity. Today, manufacturers around the world still use this strain to produce vaccines and show that the vaccine still has a good immune response.

More about the risk of inactivating the Covid-19 vaccine of the new SARS-CoV-2 variant, Prof. Dr. Ta Thanh Van, president of the Hanoi Medical University Council, said in principle in a paragraph. If the long gene is mutated, about 1,2,3 points will not affect the antigen. “That is why scientists around the world continue to make vaccines based on the original strains,” he said.

The experts also said that in some SARS-CoV-2 strains that have been recorded, the comparison of mutations will be different. However, the entire genetic segment was not affected. In addition, studies have shown that the virus strain spreads faster than the previous strain, but clinically, no more serious disease state has been recorded. There is also no difference in mortality.



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