What do the results show so far and what happens next?



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Does it differ from Pfizer and Moderna vaccines?

Yes. The Pfizer and Moderna pricks are messenger RNA (mRNA) vaccines.

Conventional vaccines are produced using weakened forms of the virus, but the mRNAs use only the genetic code of the virus.

An mRNA vaccine is injected into the body where it enters cells and tells them to create antigens.

These antigens are recognized by the immune system and prepare it to fight the coronavirus.

No virus is needed to create an mRNA vaccine. This means that the rate at which the vaccine can be produced is accelerated.

On November 20, however, Pfizer / BioNTech submitted their vaccine for emergency approval in the US They are the first pharmaceutical organization to apply for such authorization for a coronavirus vaccine, and approval would mean that the first shipment will go out. ‘ in a few hours’. This suggests that people in the UK can receive Pfizer in early to mid-December.

What about antibodies and T cells?

The Pfizer, AstraZeneca, and Moderna vaccines have been shown to elicit both an antibody and T-cell response.

Antibodies are proteins that bind to foreign invaders in the body and tell the immune system to act.

T cells are a type of white blood cell that seek out infected cells in the body and destroy them.

Almost all effective vaccines induce both responses.

The Oxford vaccine induces robust antibody and T-cell responses in people of all ages, the data indicates.

Can the Oxford vaccine be made to scale?

Yes. The UK government has secured 100 million doses as part of its contract, enough for most of the population.

UK Vaccine Task Force Head Kate Bingham has said she is confident it can be produced at scale.

Experts expect the jab to be ready and developed shortly.



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