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The UK has reported a further 533 deaths from COVID-19 and 16,578 new cases of the virus in the past 24 hours.
That compares to 12,282 cases and 616 dead on Tuesday, according to government data.
It means that the total number of people who have died in the 28 days after testing positive for the virus is now 62,566.
Live updates on coronavirus from the UK and around the world
The deaths in which COVID-19 has been mentioned on the death certificate, along with additional data on deaths that have occurred in recent days, show that there have now been 78,000 deaths related to COVID-19 in the United Kingdom.
Since the pandemic began, 1,766,819 have been confirmed coronavirus Infections
It comes as England’s chief medical officer has said that the coronavirus vaccine being rolled out in the UK reduce “substantially” deaths.
Professor Chris Whitty also said the Pfizer / BioNTech vaccine will dramatically reduce hospital admissions of COVID-19 and that there will be up to four vaccines to use by the middle of next year.
One group that is told to avoid the former is people who have a history of “significant” allergic reactions.
The advice from the Medicines and Healthcare Products Regulatory Agency (MHRA) comes after two NHS staff members who received the prick yesterday experienced allergic reactions.
They developed symptoms of an “anaphylactoid reaction” shortly after being injected, and are now known to be on the mend.
Canada has become the last country to approve the Pfizer and BioNTech coronavirus vaccine – describing it as “safe, effective and of good quality”.
In a statement, Health Canada said the authorization was a “critical milestone” in the fight against COVID-19 and noted that the review process had been “rigorous.”
The country is scheduled to receive 249,000 doses this month and four million doses by the end of March.
Overall, you have a firm order for 20 million doses of this vaccine with the option to purchase 56 million more, meaning Canada has purchased more injections per head than any other country.
Grandmother Margaret Keenan, 90, the first person in the world to receive the Pfizer vaccine, was released from the hospital.
He was given the coronavirus injection at Coventry University Hospital on Tuesday.